Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10601887 | 1.00 | LMNA (0.49) | LMNATSHRHPGDTDP1ATM | |
| SCHEMBL10601876 | 1.00 | LMNA (0.49) | LMNATSHRHPGDTDP1ATM | |
| SCHEMBL10601880 | 1.00 | LMNA (0.49) | LMNATSHRHPGDTDP1ATM | |
| SCHEMBL10995172 | 1.00 | LMNA (0.49) | LMNATSHRHPGDTDP1ATM | |
| SCHEMBL10938588 | 0.86 | LMNA (0.47) | LMNATSHRHPGDTDP1ATM | |
| SCHEMBL4433144 | 0.86 | LMNA (0.47) | LMNATSHRHPGDTDP1ATM | |
| SCHEMBL4433146 | 0.86 | LMNA (0.47) | LMNATSHRHPGDTDP1ATM | |
| SCHEMBL18783983 | 0.86 | LMNA (0.47) | LMNATSHRHPGDTDP1ATM | |
| SCHEMBL293469 | 0.86 | LMNA (0.47) | LMNATSHRHPGDTDP1ATM | |
| SCHEMBL10598336 | 0.83 | LMNA (0.68) | LMNATSHRHPGDTDP1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4496586-A | Cyclopropanecarboxylates, their production and insecticide containing them as an active ingredient | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-01-29 | — | — | US | disclosed |
| EP-0050454-A1 | New cyclopropanecarboxylates, their production and insecticide containing them as an active ingredient | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-04-28 | — | — | EP | disclosed |