SCHEMBL293469

SCHEMBL293469

COC(=O)C1C(C=C(Cl)Cl)C1(C)C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.47
TSHR P16473 3/20 0.45
KMT2A Q03164 5/20 0.43
MEN1 O00255 4/20 0.43
HTT P42858 3/20 0.43
MAPT P10636 2/20 0.43
ALDH1A1 P00352 2/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
TDP1 Q9NUW8 4/20 0.43
ATM Q13315 3/20 0.43
HPGD P15428 1/20 0.43
ADRA2A P08913 1/20 0.43
CNR1 P21554 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
POLB P06746 1/20 0.39
RAB9A P51151 1/20 0.39
CYP1A2 P05177 2/20 0.36
CYP2C19 P33261 2/20 0.36
CYP3A4 P08684 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18783983 1.00 LMNA (0.47) LMNATSHRKMT2AMEN1HTT
SCHEMBL10938588 1.00 LMNA (0.47) LMNATSHRKMT2AMEN1HTT
SCHEMBL4433144 1.00 LMNA (0.47) LMNATSHRKMT2AMEN1HTT
SCHEMBL4433146 1.00 LMNA (0.47) LMNATSHRKMT2AMEN1HTT
SCHEMBL808825 0.89 LMNA (0.49) LMNATSHRKMT2AMEN1HTT
SCHEMBL808824 0.89 LMNA (0.49) LMNATSHRKMT2AMEN1HTT
SCHEMBL808827 0.87 LMNA (0.44) LMNATSHRKMT2AMEN1HTT
SCHEMBL5706690 0.87 LMNA (0.44) LMNATSHRKMT2AMEN1HTT
SCHEMBL3358099 0.87 LMNA (0.44) LMNATSHRKMT2AMEN1HTT
SCHEMBL10995174 0.86 LMNA (0.49) LMNATSHRKMT2AMEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106152356-A A kind of band solar panels movable indoor intellectuality humidifier robot control system(RCS) and method of work thereof 徐州工程学院 2016-11-23 CN claimed
US-20070292464-A1 FIBERS AND SHEET-FORM TEXTILES PROVIDED WITH INSECT-REPELLENT FINISHES FASHION CHEMICALS GMBH & CO. KG (DE) 2007-12-20 US claimed
EP-1845186-A1 Fibres and textile sheet prepared for repelling insects Cognis IP Management GmbH (DE) 2007-10-17 EP claimed
EP-0242778-B1 SEPARATION OF DIASTEREO ISOMERS BAYER AG (DE) 1989-09-13 EP claimed
US-20260062722-A1 MODIFIED ESTERASE AMANO ENZYME INC (JP) 2026-03-05 US disclosed
EP-4506450-A1 MODIFIED ESTERASE Amano Enzyme Inc. (JP) 2025-02-12 EP disclosed
CN-119013406-A Modified esterases 天野酶制品株式会社 2024-11-22 CN disclosed
US-11119033-B2 Conformation analysis device, analysis method, conformational notation device and notation method Izumi, Hiroshi (JP) 2021-09-14 US disclosed
US-10647655-B2 Method for the synthesis of permethrin BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) 2020-05-12 US disclosed
US-10647655-B2 Method for the synthesis of permethrin BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) 2020-05-12 US disclosed
US-20190194118-A1 IMPROVED METHOD FOR THE SYNTHESIS OF PERMETHRIN BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) 2019-06-27 US disclosed
US-20190194118-A1 IMPROVED METHOD FOR THE SYNTHESIS OF PERMETHRIN BIOPHORE INDIA PHARMACEUTICALS PVT. LTD. (IN) 2019-06-27 US disclosed
US-4198343-A Method of preparing dihalogen vinyl cyclopropanecarboxylic acid esters DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1980-04-15 US disclosed
US-4198342-A Method of preparing dihalogen vinyl cyclopropanecarboxylic acid esters DYNAMIT NOBEL ATKIENGESELLSCHAFT (DE) 1980-04-15 US disclosed
US-4198341-A 2,5,5-Trimethyl-3-carbalkoxy-4(β,β-dihalovinyl)-4,5-dihydrofurans DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1980-04-15 US disclosed
US-4188492-A Process for converting 2,2-dichlorovinylcyclopropanes to dibromovinyl analogs FMC CORPORATION (US) 1980-02-12 US disclosed
US-4180446-A Method of preparing dihalogen vinyl cyclopropanecarboxylic acid esters DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1979-12-25 US disclosed
US-4166064-A 4,6,6,6 -TETRACHLORO-3,3-DIMETHYLHEXANOATE, ALKALI METAL TERT-ALKOXIDE FMC CORPORATION (US) 1979-08-28 US disclosed
EP-0003683-A2 Process for preparing high cis 3-(2,2,2-trichloroethyl)-2,2-dimethylcyclopropane-1-carboxylates FMC Corporation (US) 1979-08-22 EP disclosed
US-4113968-A FROM A 1-HALO-3-ALKENE-2-OL KURARAY CO., LTD. (JP) 1978-09-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062722-A1 MODIFIED ESTERASE CES1, BCHE, DPEP1 LMNA 1820/4885TSHR 1096/4885KMT2A 595/4885
US-20070292464-A1 FIBERS AND SHEET-FORM TEXTILES PROVIDED WITH INSECT-REPELLENT FINISHES CUTA, DBF4, MFAP1 LMNA 2480/4885TSHR 4488/4885KMT2A 2321/4885
US-10647655-B2 Method for the synthesis of permethrin NUP188, CYP2E1, AQP4 LMNA 2817/4885TSHR 2372/4885KMT2A 2522/4885
US-20190194118-A1 IMPROVED METHOD FOR THE SYNTHESIS OF PERMETHRIN CYP51A1, CYP4F3, CYP4F2 LMNA 4054/4885TSHR 3197/4885KMT2A 3025/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.