Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 2/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | GAK | O14976 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10999945 | 0.82 | ALDH1A1 (0.45) | KDM4EPTPN11ALDH1A1PIK3CAPOLB | |
| SCHEMBL10998112 | 0.80 | SMN1; SMN2 (0.46) | KDM4EPTPN11ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL10998627 | 0.78 | PIK3CA (0.52) | KDM4EMTORPTPN11ALDH1A1PIK3CA | |
| SCHEMBL11002348 | 0.78 | PTPN11 (0.47) | ACHEKDM4EPTPN11ALDH1A1PIK3CA | |
| SCHEMBL11002487 | 0.78 | ALDH1A1 (0.44) | ACHEKDM4EALDH1A1SMN1; SMN2HRH4 | |
| SCHEMBL10996942 | 0.77 | PTPN11 (0.36) | KDM4EPTPN11ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL28648225 | 0.76 | AOC3 (0.41) | CDK1CDK2ACHEKDM4EOPRL1 | |
| SCHEMBL11000736 | 0.76 | PTPN11 (0.53) | ACHEOPRL1OPRM1PTPN11POLB | |
| SCHEMBL10996681 | 0.75 | PIK3CD (0.32) | PTPN11ALDH1A1PIK3CAPOLBSMN1; SMN2 | |
| SCHEMBL11000227 | 0.74 | MAPT (0.55) | PTPN11ALDH1A1POLBSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE31926-E | Penicillins and salts thereof | BOEHRINGER INGELHEIM GMBH (DE) | 1985-06-25 | — | — | US | disclosed |
| US-4241056-A | ANTIBIOTICS | BOEHRINGER INGELHEIM GMBH (DE) | 1980-12-23 | — | — | US | disclosed |