Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 9/20 | 0.52 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.52 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | PIK3R1 | P27986 | 6/20 | 0.49 |
| ▸ | MTOR | P42345 | 6/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10999945 | 0.84 | ALDH1A1 (0.45) | PIK3CAPIK3CDPIK3CBKDM4EPOLB | |
| SCHEMBL10998112 | 0.83 | SMN1; SMN2 (0.46) | KDM4EPOLBALDH1A1MAPK1PTPN11 | |
| SCHEMBL27586071 | 0.83 | KDM4E (0.54) | PIK3CAPIK3CDPIK3CBKDM4EPIK3R1 | |
| SCHEMBL11002348 | 0.80 | PTPN11 (0.47) | PIK3CAPIK3CDPIK3CBKDM4EPOLB | |
| SCHEMBL11002487 | 0.80 | ALDH1A1 (0.44) | KDM4EKMT2AALDH1A1TSHR | |
| SCHEMBL11000227 | 0.80 | MAPT (0.55) | POLBKMT2AALDH1A1MAPK1PTPN11 | |
| SCHEMBL10995352 | 0.78 | CDK1 (0.40) | PIK3CAPIK3CDPIK3CBKDM4EMTOR | |
| SCHEMBL10996681 | 0.78 | PIK3CD (0.32) | PIK3CAPIK3CDPIK3CBPOLBALDH1A1 | |
| SCHEMBL10328269 | 0.76 | PIK3CA (0.64) | PIK3CAPIK3CDPIK3CBPIK3R1MTOR | |
| SCHEMBL10996942 | 0.76 | PTPN11 (0.36) | KDM4EPOLBALDH1A1MAPK1PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE31926-E | Penicillins and salts thereof | BOEHRINGER INGELHEIM GMBH (DE) | 1985-06-25 | — | — | US | disclosed |
| EP-0003814-B1 | PENICILLINS, THEIR SALTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1981-12-16 | — | — | EP | disclosed |
| US-4241056-A | ANTIBIOTICS | BOEHRINGER INGELHEIM GMBH (DE) | 1980-12-23 | — | — | US | disclosed |
| EP-0003814-A2 | Penicillins, their salts, process for their preparation and pharmaceutical compositions containing them | Dr. Karl Thomae GmbH (DE) | 1979-09-05 | — | — | EP | disclosed |