Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GPR183 | P32249 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | BCR | P11274 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL694171 | 0.83 | HPGD (0.63) | PKMHPGDCA12CA1CA2 | |
| SCHEMBL10997891 | 0.81 | PKM (0.69) | PKMHPGD | |
| SCHEMBL28396337 | 0.74 | HPGD (0.61) | HPGDCA12CA1CA2CA7 | |
| SCHEMBL971083 | 0.73 | HPGD (1.00) | HPGDCA12CA1CA2CA7 | |
| SCHEMBL644199 | 0.73 | HPGD (0.92) | HPGDCA12CA1CA2CA7 | |
| SCHEMBL24185226 | 0.73 | HPGD (0.59) | HPGDCA12CA1CA2CA7 | |
| SCHEMBL13600346 | 0.73 | HPGD (0.70) | HPGDCA12CA1CA2CA7 | |
| SCHEMBL26987208 | 0.73 | HPGD (0.70) | HPGDCA12CA1CA2CA7 | |
| SCHEMBL15758285 | 0.73 | HPGD (0.59) | HPGDCA12CA1CA2CA7 | |
| Hydrochloric Acid SCHEMBL21590292 | 0.72 | HPGD (0.89) | HPGDCA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4523013-A | 4-Acyl-2,6-dioxo-1-phenethyl piperozines | SANOFI, S.A. (FR) | 1985-06-11 | — | — | US | disclosed |