Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.83 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | HPGD | P15428 | 5/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | ALB | P02768 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.55 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.55 |
| ▸ | TUBB | P07437 | 1/20 | 0.55 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.55 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.55 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.55 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.55 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.55 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.55 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11185046 | 0.93 | LMNA (0.85) | LMNAKDM4ESMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL10994613 | 0.92 | LMNA (0.87) | LMNAKDM4ESMN1; SMN2CYP1A2ALDH1A1 | |
| SCHEMBL11000799 | 0.92 | LMNA (0.83) | LMNAKDM4ESMN1; SMN2CYP1A2ALDH1A1 | |
| Nadifloxacin SCHEMBL3818938 | 0.91 | LMNA (1.00) | LMNAKDM4ESMN1; SMN2CYP1A2ALDH1A1 | |
| Vebufloxacin SCHEMBL29391678 | 0.91 | LMNA (0.82) | LMNAKDM4ESMN1; SMN2CYP1A2ALDH1A1 | |
| Nadifloxacin SCHEMBL29429713 | 0.91 | LMNA (1.00) | LMNAKDM4ESMN1; SMN2CYP1A2ALDH1A1 | |
| Nadifloxacin SCHEMBL36593 | 0.91 | LMNA (1.00) | LMNAKDM4ESMN1; SMN2CYP1A2ALDH1A1 | |
| Levonadifloxacin SCHEMBL36594 | 0.91 | LMNA (1.00) | LMNAKDM4ESMN1; SMN2CYP1A2ALDH1A1 | |
| Vebufloxacin SCHEMBL866602 | 0.91 | LMNA (0.82) | LMNAKDM4ESMN1; SMN2CYP1A2ALDH1A1 | |
| Levonadifloxacin SCHEMBL29390463 | 0.91 | LMNA (1.00) | LMNAKDM4ESMN1; SMN2CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4552879-A | BACTERICIDES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-11-12 | — | — | US | disclosed |
| US-4399134-A | BACTERICIDES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1983-08-16 | — | — | US | disclosed |