Vebufloxacin

Vebufloxacin

SCHEMBL866602

CC1CCc2c(N3CCN(C)CC3)c(F)cc3c(=O)c(C(=O)O)cn1c23

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.82
KDM4E B2RXH2 12/20 0.68
ALDH1A1 P00352 7/20 0.68
HPGD P15428 6/20 0.68
HSD17B10 Q99714 4/20 0.68
ALB P02768 1/20 0.68
HRH3 Q9Y5N1 1/20 0.68
POLB P06746 2/20 0.67
TUBB4A P04350 1/20 0.67
TUBB P07437 1/20 0.67
TUBA3C P0DPH7 1/20 0.67
TUBA1B P68363 1/20 0.67
TUBA4A P68366 1/20 0.67
TUBB4B P68371 1/20 0.67
TUBB3 Q13509 1/20 0.67
TUBB2A Q13885 1/20 0.67
TUBB8 Q3ZCM7 1/20 0.67
TUBA3E Q6PEY2 1/20 0.67
TUBA1A Q71U36 1/20 0.67
SLC47A1 Q96FL8 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Vebufloxacin SCHEMBL29391678 1.00 LMNA (0.82) LMNAKDM4EALDH1A1HPGDHSD17B10
Vebufloxacin SCHEMBL11160410 0.98 LMNA (0.79) LMNAKDM4EALDH1A1HPGDHSD17B10
SCHEMBL11185046 0.92 LMNA (0.85) LMNAKDM4EALDH1A1HPGDHSD17B10
SCHEMBL11000799 0.91 LMNA (0.83) LMNAKDM4EALDH1A1HPGDHSD17B10
SCHEMBL10995672 0.91 LMNA (0.83) LMNAKDM4EALDH1A1HPGDHSD17B10
SCHEMBL10994613 0.91 LMNA (0.87) LMNAKDM4EALDH1A1HPGDHSD17B10
SCHEMBL11163121 0.91 LMNA (0.76) LMNAKDM4EALDH1A1HPGDHSD17B10
SCHEMBL11169414 0.90 LMNA (0.79) LMNAKDM4EALDH1A1HPGDHSD17B10
Nadifloxacin SCHEMBL3818938 0.90 LMNA (1.00) LMNAKDM4EALDH1A1HPGDHSD17B10
Levonadifloxacin SCHEMBL36594 0.90 LMNA (1.00) LMNAKDM4EALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230285572-A1 TARGETED DELIVERY OF THERAPEUTIC AGENTS SEPELO THERAPEUTICS, LLC 2023-09-14 US claimed
EP-4188433-A2 TARGETED DELIVERY OF THERAPEUTIC AGENTS Sepelo Therapeutics, LLC (US) 2023-06-07 EP claimed
WO-2023028364-A1 TARGETED COMPOSITIONS AND USES THEROF SEPELO THERAPEUTICS, LLC (US) 2023-03-02 WO claimed
WO-2022031761-A2 TARGETED DELIVERY OF THERAPEUTIC AGENTS SEPELO THERAPEUTICS, LLC (US) 2022-02-10 WO claimed
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
US-4416884-A ANTIBIOTIC, BACTERICIDE OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1983-11-22 US claimed
EP-3782649-B1 BIODEGRADABLE POLYETHYLENE GLYCOL BASED WATER-INSOLUBLE HYDROGELS ASCENDIS PHARMA AS (DK) 2025-05-14 EP disclosed
US-20230381323-A1 RELEASABLE CONJUGATES FISH & RICHARDSON PC 2023-11-30 US disclosed
EP-3752201-B1 SUSPENSION OF NANOSCALE, ORGANIC PARTICLES AND PROCESS FOR PRODUCTION THEREOF UNIV FRIEDRICH ALEXANDER ER (DE) 2023-11-22 EP disclosed
US-11786599-B2 Releasable conjugates QUIAPEG PHARMACEUTICALS AB (SE) 2023-10-17 US disclosed
EP-0047005-B1 BENZOXAZINE DERIVATIVES DAIICHI SEIYAKU CO., LTD. (JP) 1984-11-14 EP disclosed
EP-0101829-A2 Tricyclic compounds, a process for their production and pharmaceutical compositions containing said compounds DAIICHI SEIYAKU CO., LTD. (JP) 1984-03-07 EP disclosed
US-4416884-A ANTIBIOTIC, BACTERICIDE OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1983-11-22 US disclosed
US-4382892-A Benzoxazine derivatives DAIICHI SEIYAKU CO., LTD. (JP) 1983-05-10 US disclosed
EP-0047005-A1 Benzoxazine derivatives DAIICHI SEIYAKU CO., LTD. (JP) 1982-03-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230381323-A1 RELEASABLE CONJUGATES GUSB, ABCB11, UGT2B7 LMNA 2176/4885KDM4E 3590/4885ALDH1A1 72/4885
US-11786599-B2 Releasable conjugates GUSB, ABCB11, UGT2B7 LMNA 2176/4885KDM4E 3590/4885ALDH1A1 72/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.