Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | CASP1 | P29466 | 2/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | BAP1 | Q92560 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7273183 | 0.89 | HSD17B10 (0.41) | HSD17B10ALDH1A1HPGDCASP1CASP7 | |
| SCHEMBL10998214 | 0.85 | CYP2C9 (0.56) | HSD17B10ALDH1A1HPGDTSHRKDM4E | |
| SCHEMBL10996510 | 0.84 | HSD17B10 (0.52) | HSD17B10ALDH1A1HPGDCASP1CASP7 | |
| SCHEMBL10998379 | 0.81 | CACNA1C (0.54) | HSD17B10ALDH1A1HPGDTSHRKDM4E | |
| SCHEMBL10995581 | 0.79 | CACNA1B (0.51) | TSHRMAPTKMT2ACYP2C9MEN1 | |
| SCHEMBL11001195 | 0.77 | ALDH1A1 (0.54) | HSD17B10ALDH1A1HPGDTSHRKDM4E | |
| SCHEMBL10996142 | 0.77 | MEN1 (0.65) | TSHRMAPTKMT2APOLBCYP2C9 | |
| SCHEMBL10995886 | 0.76 | KDM4E (0.51) | HSD17B10ALDH1A1HPGDTSHRKDM4E | |
| SCHEMBL10999558 | 0.76 | KDM4E (0.56) | HSD17B10ALDH1A1HPGDTSHRKDM4E | |
| SCHEMBL10994856 | 0.74 | KDM4E (0.61) | HSD17B10ALDH1A1HPGDTSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4558058-A | HYPOTENSIVE AGENTS | CASSELLA AKTIENGESELLSCHAFT (DE) | 1985-12-10 | — | — | US | disclosed |