Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.46 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.46 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.46 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8827588 | 0.87 | GNAI3 (0.62) | SMN1; SMN2GNAI3GNAO1GNAI1ALDH1A1 | |
| SCHEMBL20581686 | 0.86 | SMN1; SMN2 (0.56) | SMN1; SMN2MTNR1AMTNR1BGNAI3GNAO1 | |
| SCHEMBL5988081 | 0.86 | — | — | |
| SCHEMBL14199968 | 0.86 | SMN1; SMN2 (0.56) | SMN1; SMN2MTNR1AMTNR1BGNAI3GNAO1 | |
| SCHEMBL1489877 | 0.84 | MTNR1A (0.44) | SMN1; SMN2MTNR1AMTNR1BGNAI3GNAO1 | |
| SCHEMBL20999175 | 0.82 | SMN1; SMN2 (0.63) | SMN1; SMN2MTNR1AMTNR1BGNAI3GNAO1 | |
| SCHEMBL2752779 | 0.82 | SMN1; SMN2 (0.69) | SMN1; SMN2MTNR1AMTNR1BGNAI3GNAO1 | |
| SCHEMBL931479 | 0.80 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL11804456 | 0.80 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1HPGDMAPTKMT2A | |
| Hydrochloric Acid SCHEMBL27942584 | 0.80 | SMN1; SMN2 (0.61) | SMN1; SMN2MTNR1AMTNR1BGNAI3GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4552879-A | BACTERICIDES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-11-12 | — | — | US | disclosed |
| US-4399134-A | BACTERICIDES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1983-08-16 | — | — | US | disclosed |