Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | HPGD | P15428 | 5/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.59 |
| ▸ | ALB | P02768 | 1/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 4/20 | 0.58 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.58 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.58 |
| ▸ | TUBB | P07437 | 1/20 | 0.58 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.58 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.58 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.58 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.58 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.58 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.58 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.58 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.58 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11000457 | 0.99 | LMNA (0.67) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9582683 | 0.92 | KDM4E (0.71) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9581753 | 0.92 | KDM4E (0.71) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9034716 | 0.92 | KDM4E (0.71) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL9035040 | 0.91 | KDM4E (0.69) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL9582997 | 0.91 | KDM4E (0.69) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10996775 | 0.91 | LMNA (0.65) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10999003 | 0.91 | LMNA (0.65) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10998004 | 0.91 | LMNA (0.83) | LMNAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL10993045 | 0.91 | LMNA (0.65) | LMNAKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57176987-A | — | — | None | — | — | JP | disclosed |
| US-4552879-A | BACTERICIDES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-11-12 | — | — | US | disclosed |
| US-4399134-A | BACTERICIDES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1983-08-16 | — | — | US | disclosed |
| JP-S57176987-A | PYRROLO(3,2,1-IJ)QUINOLINE-5-CARBOXYLIC ACID DERIVATIVE | OTSUKA PHARMACEUT CO LTD | 1982-10-30 | — | — | JP | disclosed |