Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.71 |
| ▸ | HPGD | P15428 | 4/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.71 |
| ▸ | ALB | P02768 | 1/20 | 0.71 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.71 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | TUBB | P07437 | 1/20 | 0.69 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.69 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.69 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.69 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.69 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.69 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.69 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.69 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.69 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.69 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.69 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9582683 | 1.00 | KDM4E (0.71) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL9581753 | 1.00 | KDM4E (0.71) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| Hydrochloric Acid SCHEMBL9035040 | 0.99 | KDM4E (0.69) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| Hydrochloric Acid SCHEMBL9582997 | 0.99 | KDM4E (0.69) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL10996910 | 0.92 | LMNA (0.68) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL11000457 | 0.91 | LMNA (0.67) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| Vebufloxacin SCHEMBL29391678 | 0.90 | LMNA (0.82) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| Vebufloxacin SCHEMBL866602 | 0.90 | LMNA (0.82) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL10997327 | 0.89 | LMNA (0.63) | KDM4EALDH1A1HPGDHSD17B10ALB | |
| SCHEMBL9033947 | 0.89 | LMNA (0.60) | KDM4EALDH1A1HPGDHSD17B10ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0390135-B1 | Pyrroloquinoline derivatives, antimicrobial agents using the same and process for preparing the same | OTSUKA PHARMA CO LTD (JP) | 1996-06-05 | — | — | EP | claimed |
| US-5185337-A | Pyrroloquinoline derivatives and pharmaceutical compositions for antimicrobial use | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-09 | — | — | US | claimed |
| US-4416884-A | ANTIBIOTIC, BACTERICIDE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1983-11-22 | — | — | US | claimed |
| JP-4139126-A | — | — | None | — | — | JP | disclosed |
| EP-0390135-B1 | Pyrroloquinoline derivatives, antimicrobial agents using the same and process for preparing the same | OTSUKA PHARMA CO LTD (JP) | 1996-06-05 | — | — | EP | disclosed |
| US-5185337-A | Pyrroloquinoline derivatives and pharmaceutical compositions for antimicrobial use | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-09 | — | — | US | disclosed |
| JP-H04139126-A | ANTIBACTERIAL AGENT | OTSUKA PHARMACEUT CO LTD | 1992-05-13 | — | — | JP | disclosed |
| EP-0390135-A1 | Pyrroloquinoline derivatives, antimicrobial agents using the same and process for preparing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-03 | — | — | EP | disclosed |
| EP-0115334-B1 | BENZO-HETEROCYCLIC COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-07-22 | — | — | EP | disclosed |
| US-4594347-A | MICROBIOCIDES | OTSUKA PHARMACEUTICAL CO. LIMITED (JP) | 1986-06-10 | — | — | US | disclosed |
| EP-0115334-A1 | Benzo-heterocyclic compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-08-08 | — | — | EP | disclosed |
| US-4416884-A | ANTIBIOTIC, BACTERICIDE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1983-11-22 | — | — | US | disclosed |