Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 7/20 | 0.41 |
| ▸ | TOP2B | Q02880 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10782548 | 0.88 | LMNA (0.68) | KDM4ESMN1; SMN2CYP1A2LMNAKMT2A | |
| SCHEMBL11745459 | 0.88 | KDM4E (0.57) | KDM4ESMN1; SMN2CYP1A2LMNAKMT2A | |
| SCHEMBL9582926 | 0.88 | KDM4E (0.50) | KDM4ESMN1; SMN2CYP1A2LMNAKMT2A | |
| SCHEMBL9036111 | 0.88 | KDM4E (0.50) | KDM4ESMN1; SMN2CYP1A2LMNAKMT2A | |
| SCHEMBL11745221 | 0.85 | KDM4E (0.53) | KDM4ESMN1; SMN2CYP1A2LMNAKMT2A | |
| SCHEMBL10998820 | 0.84 | KDM4E (0.55) | KDM4ESMN1; SMN2CYP1A2LMNAKMT2A | |
| SCHEMBL11000397 | 0.84 | LMNA (0.65) | KDM4ESMN1; SMN2CYP1A2LMNAKMT2A | |
| SCHEMBL11162090 | 0.83 | LMNA (0.64) | KDM4ESMN1; SMN2CYP1A2LMNATOP2A | |
| SCHEMBL11165938 | 0.82 | LMNA (0.63) | KDM4ESMN1; SMN2CYP1A2LMNATOP2A | |
| SCHEMBL11001513 | 0.82 | LMNA (0.55) | KDM4ESMN1; SMN2CYP1A2LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-56055388-A | — | — | None | — | — | JP | disclosed |
| US-4552879-A | BACTERICIDES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-11-12 | — | — | US | disclosed |
| US-4416884-A | ANTIBIOTIC, BACTERICIDE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1983-11-22 | — | — | US | disclosed |
| US-4399134-A | BACTERICIDES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1983-08-16 | — | — | US | disclosed |
| JP-S5655388-A | BENZO IJ QUINOLIDINE-2-CARBOXYLIC ACID DERIVATIVE, AND ITS PREPARATION | OTSUKA PHARMACEUT CO LTD | 1981-05-15 | — | — | JP | disclosed |