Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA2 | P16389 | 3/20 | 0.61 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.61 |
| ▸ | KCNA1 | Q09470 | 3/20 | 0.61 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.56 |
| ▸ | KCNA4 | P22459 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7795939 | 0.79 | KCNA3 (0.56) | KCNA2KCNA5KCNA1KCNA3 | |
| SCHEMBL7796134 | 0.79 | KCNA3 (0.56) | KCNA2KCNA5KCNA1KCNA3 | |
| SCHEMBL30375567 | 0.79 | MAOB (0.50) | KCNA3 | |
| SCHEMBL16246347 | 0.79 | MAOB (0.50) | KCNA3 | |
| SCHEMBL8052928 | 0.78 | MAPT (0.50) | KCNA2KCNA5KCNA1KCNA3 | |
| SCHEMBL21217354 | 0.77 | PDE4A (0.57) | KCNA3 | |
| SCHEMBL678486 | 0.77 | KCNA3 (0.53) | KCNA2KCNA5KCNA1KCNA3KCNA4 | |
| SCHEMBL27389746 | 0.75 | MAPT (0.53) | KCNA3 | |
| SCHEMBL16060697 | 0.75 | MGAM (0.50) | KCNA2KCNA5KCNA1KCNA3 | |
| SCHEMBL29929467 | 0.75 | KCNA3 (0.67) | KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4532254-A | Inhibitor of aldose reductase | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1985-07-30 | — | — | US | disclosed |