Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 2/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | KCNA2 | P16389 | 1/20 | 0.48 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.48 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7796134 | 0.94 | KCNA3 (0.56) | KCNA3PTPN1KCNA2KCNA5KCNA1 | |
| SCHEMBL7796139 | 0.92 | PTPN1 (0.54) | KCNA3PTPN1KCNA2KCNA5KCNA1 | |
| SCHEMBL7786636 | 0.87 | PTPN1 (0.49) | KCNA3PTPN1KCNA2KCNA5KCNA1 | |
| SCHEMBL31643912 | 0.85 | KCNA3 (0.49) | KCNA3PTPN1SMN1; SMN2MAPTCYP2C9 | |
| SCHEMBL31644176 | 0.82 | LMNA (0.57) | KCNA3PTPN1MAPTTDP1L3MBTL1 | |
| SCHEMBL13233013 | 0.80 | PTPN1 (0.52) | PTPN1SMN1; SMN2MAPTCYP2C9CYP2C19 | |
| SCHEMBL10998626 | 0.79 | KCNA2 (0.61) | KCNA3KCNA2KCNA5KCNA1 | |
| SCHEMBL8593396 | 0.79 | PSMG3 (0.48) | KCNA3PTPN1LMNAHPGD | |
| SCHEMBL31643593 | 0.79 | KCNA3 (0.45) | KCNA3PTPN1SMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL24968079 | 0.79 | L3MBTL1 (0.63) | PTPN1SMN1; SMN2MAPTCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0909267-B1 | NOVEL 1,3-DIPHENYLPROPANE DERIVATIVES HAVING INHIBITORY ACTIVITY AGAINST TYROSINASE AND PROCESS FOR PREPARATION THEREOF | LG CHEMICAL LTD (KR) | 2001-11-21 | — | — | EP | disclosed |
| US-6093836-A | INHIBITORY ACTIVITY AGAINT MELANIN BIOSYNTHESIS; WHITENING SUBSTANCES FOR MEDICAMENTS, COSMETICS | LG CHEMICAL LTD. (KR) | 2000-07-25 | — | — | US | disclosed |