SCHEMBL1099885

SCHEMBL1099885

N#CC(C#N)=C1CCC=CO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1101204 0.77
SCHEMBL28930323 0.71
SCHEMBL22826529 0.67 ALDH1A1 (0.39)
SCHEMBL31483416 0.61 EGFR (0.30)
SCHEMBL1099883 0.61
SCHEMBL10791093 0.58
SCHEMBL29141813 0.56 ALDH1A1 (0.38)
SCHEMBL2786474 0.56 ALDH1A1 (0.46)
SCHEMBL24798951 0.56 EGFR (0.34)
SCHEMBL19973082 0.55 ALDH1A1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120157663-A Dicyanomethylene-4H-pyran fluorescent probe VisDCM and preparation method and application thereof 南京师范大学 2025-06-17 CN claimed
CN-120157664-A Fluorescent probe based on dicyanomethylene-4H-pyran and preparation method and application thereof 南京师范大学 2025-06-17 CN claimed
CN-118903481-A ER alpha targeted PEGylated near infrared fluorescent probe and preparation method and application thereof 武昌理工学院 2024-11-08 CN claimed
WO-2024121871-A1 GENETIC MODIFICATION OF MICROBES FOR PRODUCTION OF NITROGEN AND CARBON-CONTAINING COMPOUNDS FERTIS INDIA PVT. LTD. (IN) 2024-06-13 WO claimed
CN-111714456-A Target and fluorescent tracing multifunctional nano vesicle drug-loading system with stimulation responsiveness 西北农林科技大学 2020-09-29 CN claimed
CN-107382982-B dicyanomethylene-4H-pyran derivative and preparation method and application thereof 温州大学 2020-07-31 CN claimed
US-20260027243-A1 AMPHIPHILIC COMPOUNDS FOR ATTENUATING NEUROTOXICITY OF AMYLOID-beta OLIGOMERS AND DIAGNOSTIC METHODS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2026-01-29 US disclosed
CN-120842203-B Preparation method and application of near infrared fluorescent probe for specifically detecting SHP2 山东大学 2025-12-05 CN disclosed
CN-120842203-A Preparation method and application of near infrared fluorescent probe for specifically detecting SHP2 山东大学 2025-10-28 CN disclosed
CN-120271506-A Cytochrome oxidase P450 fluorescent probe based on olefin epoxidation elimination and application thereof 湖南大学 2025-07-08 CN disclosed
CN-120209078-A Pentapeptide complex fluorescent probe and application thereof in distinguishing pre-injury from post-death injury 复旦大学 2025-06-27 CN disclosed
CN-120157664-A Fluorescent probe based on dicyanomethylene-4H-pyran and preparation method and application thereof 南京师范大学 2025-06-17 CN disclosed
CN-120157664-A Fluorescent probe based on dicyanomethylene-4H-pyran and preparation method and application thereof 南京师范大学 2025-06-17 CN disclosed
US-20100029952-A1 Fluorogenic compounds converted to fluorophores by photochemical or chemical means and their use in biological systems KENT STATE UNIVERSITY (US) 2010-02-04 US disclosed
US-7453204-B2 Light emitting element with light-emitting material in different concentrations FUJIFILM CORPORATION (JP) 2008-11-18 US disclosed
US-7364804-B2 Pyran derivative, method for manufacturing the same, and light-emitting element containing the pyran derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-04-29 US disclosed
WO-2007017179-A1 USE OF IONIC UV-A SUNSCREENS DSM IP ASSETS B.V. (NL) 2007-02-15 WO disclosed
US-20060181197-A1 Electroluminescent device and display MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2006-08-17 US disclosed
US-20050184655-A1 Light emitting element FUJI PHOTO FILM CO., LTD. (JP) 2005-08-25 US disclosed
US-20050048315-A1 Pyran derivative, method for manufacturing the same, and light-emitting element containing the pyran derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2005-03-03 US disclosed