Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 14/20 | 0.53 |
| ▸ | CACNA1D | Q01668 | 14/20 | 0.53 |
| ▸ | CACNA1S | Q13698 | 14/20 | 0.53 |
| ▸ | CACNA1C | Q13936 | 14/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10785375 | 0.88 | CACNA1F (0.68) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL10503428 | 0.86 | CACNA1C (0.47) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL11005053 | 0.85 | SMN1; SMN2 (0.48) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL10502815 | 0.84 | CACNA1F (0.55) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL11034438 | 0.83 | CACNA1D (0.44) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL10509327 | 0.80 | CACNA1F (0.52) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL11371616 | 0.79 | CACNA1F (0.66) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL6425850 | 0.79 | MEN1 (0.67) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL10503261 | 0.79 | CYP2C9 (0.48) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 | |
| SCHEMBL11168014 | 0.78 | CACNA1F (0.62) | CACNA1FCACNA1DCACNA1SCACNA1CADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0133530-A2 | 1,6-Naphthyridinone derivatives, process for their preparation, and medicaments containing them | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1985-02-27 | — | — | EP | disclosed |