Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CCR5 | P51681 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27590304 | 0.90 | TSHR (0.53) | MMP12TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7999122 | 0.88 | TSHR (0.66) | TSHRMEN1KMT2ACCR5SMN1; SMN2 | |
| SCHEMBL350869 | 0.86 | TSHR (0.63) | TSHRMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL1536704 | 0.85 | TSHR (0.54) | TSHRMEN1KMT2ACCR5SMN1; SMN2 | |
| SCHEMBL14896389 | 0.83 | TSHR (0.51) | TSHRMEN1KMT2ACCR5SMN1; SMN2 | |
| SCHEMBL17986241 | 0.81 | TSHR (0.58) | TSHRMEN1KMT2ACCR5SMN1; SMN2 | |
| SCHEMBL8041387 | 0.81 | TSHR (0.58) | TSHRMEN1KMT2ACCR5SMN1; SMN2 | |
| SCHEMBL11239432 | 0.80 | TSHR (0.56) | TSHRMEN1KMT2ACCR5SMN1; SMN2 | |
| SCHEMBL135651 | 0.79 | TSHR (0.59) | TSHRMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL6585903 | 0.79 | LMNA (0.54) | TSHRMEN1KMT2ACCR5SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4525582-A | Silyl, benzyl, p-nitrobenyl, or methyl esters of diazoacetate, a synthon used in the conversion of penicillin to thienamycin | MERCK & CO., INC. (US) | 1985-06-25 | — | — | US | disclosed |