Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | BCL9 | O00512 | 1/20 | 0.54 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.54 |
| ▸ | IAPP | P10997 | 1/20 | 0.53 |
| ▸ | CCR5 | P51681 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7999122 | 0.91 | TSHR (0.66) | TSHRCCR5ALDH1A1KCNH2MAPT | |
| SCHEMBL8041387 | 0.88 | TSHR (0.58) | TSHRBCL9CTNNB1IAPPCCR5 | |
| SCHEMBL16995172 | 0.88 | ALDH1A1 (0.59) | TSHRBCL9CTNNB1IAPPCCR5 | |
| SCHEMBL8934567 | 0.85 | ALDH1A1 (0.58) | TSHRBCL9CTNNB1ALDH1A1MAPT | |
| SCHEMBL1536704 | 0.82 | TSHR (0.54) | TSHRCCR5ALDH1A1KCNH2MAPT | |
| SCHEMBL1312170 | 0.81 | KCNH2 (0.60) | TSHRBCL9CTNNB1IAPPALDH1A1 | |
| SCHEMBL17986241 | 0.81 | TSHR (0.58) | TSHRCCR5ALDH1A1KCNH2MAPT | |
| SCHEMBL8855273 | 0.81 | TSHR (0.61) | TSHRALDH1A1KCNH2MAPTMEN1 | |
| SCHEMBL10999840 | 0.80 | MMP12 (0.58) | TSHRCCR5ALDH1A1KCNH2MAPT | |
| SCHEMBL670267 | 0.80 | TSHR (0.64) | TSHRALDH1A1KCNH2MAPTKCNJ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336269-A | ANTIARRHYTHMIA | ELI LILLY AND COMPANY (US) | 1982-06-22 | — | — | US | disclosed |
| US-4277501-A | ANTIARRHYTHMIA AGENTS | ELI LILLY AND COMPANY (US) | 1981-07-07 | — | — | US | disclosed |