Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 8/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6564484 | 1.00 | TSHR (0.40) | TSHRTHRBTRPM8DNM1OPRM1 | |
| SCHEMBL5561432 | 0.91 | TRPM8 (0.33) | TSHRTHRBTRPM8DNM1 | |
| SCHEMBL11230622 | 0.91 | TRPM8 (0.33) | TSHRTHRBTRPM8DNM1 | |
| SCHEMBL164254 | 0.90 | — | — | |
| SCHEMBL9577626 | 0.87 | TSHR (0.32) | TSHRTRPM8LMNA | |
| SCHEMBL11532056 | 0.81 | LMNA (0.39) | LMNA | |
| SCHEMBL11189521 | 0.81 | — | — | |
| SCHEMBL10757392 | 0.79 | — | — | |
| SCHEMBL11616978 | 0.79 | TSHR (0.44) | TSHRTHRBTRPM8DNM1OPRM1 | |
| SCHEMBL8511451 | 0.79 | TSHR (0.44) | TSHRTHRBTRPM8DNM1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4547475-A | LOW TEMPERATURE REACTION OF MAGNESIUM COMPOUND AND NON-METALLIC HALIDE | THE DOW CHEMICAL COMPANY (US) | 1985-10-15 | — | — | US | claimed |