Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7731446 | 0.83 | LMNA (0.47) | ESR1ESR2CYP3A4NFKB1PMP22 | |
| SCHEMBL6677192 | 0.83 | CYP3A4 (0.48) | ESR1ESR2CYP3A4NFKB1PMP22 | |
| SCHEMBL2891199 | 0.78 | ATM (0.49) | ESR1ESR2CYP3A4LMNASCN2A | |
| SCHEMBL11863055 | 0.78 | ESR1 (0.57) | ESR1ESR2CYP3A4NFKB1PMP22 | |
| SCHEMBL11305617 | 0.78 | ESR1 (0.57) | ESR1ESR2CYP3A4NFKB1PMP22 | |
| SCHEMBL29126967 | 0.78 | GRIK1 (0.51) | CYP3A4LMNAALDH1A1MAPTHTT | |
| SCHEMBL30657596 | 0.78 | GRIK1 (0.51) | CYP3A4LMNAALDH1A1MAPTHTT | |
| SCHEMBL4198055 | 0.78 | LMNA (0.56) | ESR1ESR2LMNASCN2ARECQL | |
| SCHEMBL3843730 | 0.77 | CYP3A4 (0.57) | ESR1ESR2CYP3A4NFKB1PMP22 | |
| SCHEMBL5846779 | 0.74 | LMNA (0.61) | ESR1ESR2LMNASCN2ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4552879-A | BACTERICIDES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-11-12 | — | — | US | disclosed |
| US-4399134-A | BACTERICIDES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1983-08-16 | — | — | US | disclosed |