Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | MMP14 | P50281 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | GCGR | P47871 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | GALR2 | O43603 | 1/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | CCR6 | P51684 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28806062 | 0.88 | ESR1 (0.46) | MMP2MMP13MMP14ALDH1A1SMN1; SMN2 | |
| SCHEMBL26189280 | 0.85 | NR4A2 (0.51) | POLBKMT2AMAPTCYP11B1CYP11B2 | |
| SCHEMBL12466331 | 0.82 | L3MBTL1 (0.42) | ALDH1A1KMT2AKDM4EMEN1AGTR1 | |
| SCHEMBL28011463 | 0.80 | L3MBTL1 (0.40) | ALDH1A1KMT2AKDM4EMEN1AGTR1 | |
| SCHEMBL10475570 | 0.79 | CYP11B1 (0.46) | SMN1; SMN2POLBKMT2AMEN1MAPT | |
| SCHEMBL16529634 | 0.79 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2HPGDNPSR1GALR2 | |
| SCHEMBL2126420 | 0.78 | CA12 (0.62) | ALDH1A1SMN1; SMN2HPGDNPSR1GALR2 | |
| SCHEMBL11002921 | 0.78 | CYP11B1 (0.45) | SMN1; SMN2POLBKMT2AMEN1MAPT | |
| Potassium Ion SCHEMBL11002916 | 0.78 | CYP11B1 (0.42) | ALDH1A1SMN1; SMN2POLBKMT2AMEN1 | |
| SCHEMBL6422578 | 0.78 | KMT2A (0.65) | ALDH1A1SMN1; SMN2HPGDNPSR1GALR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4552966-A | 2-Nitro-4-(4-pyridinyl) benzoic acids and derivatives | ETHYL CORPORATION (US) | 1985-11-12 | — | — | US | claimed |