SCHEMBL11001060

SCHEMBL11001060

Cc1ccc(CN(C)c2ccccc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRHBP P24387 1/20 0.59
CRHR2 Q13324 1/20 0.59
CYP2C19 P33261 1/20 0.57
CNR2 P34972 2/20 0.47
NR1H2 P55055 1/20 0.47
NR1H3 Q13133 1/20 0.47
HDAC3 O15379 1/20 0.47
HDAC1 Q13547 1/20 0.47
HDAC2 Q92769 1/20 0.47
NCOR2 Q9Y618 1/20 0.47
TSHR P16473 2/20 0.46
ALDH1A1 P00352 1/20 0.46
TAAR1 Q96RJ0 3/20 0.45
CNR1 P21554 1/20 0.44
PYCR1 P32322 1/20 0.44
AOC3 Q16853 1/20 0.43
CA12 O43570 1/20 0.43
CA9 Q16790 1/20 0.43
CYP19A1 P11511 1/20 0.43
NPSR1 Q6W5P4 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14948318 0.93 CYP2C19 (0.55) CRHBPCRHR2CYP2C19CNR2NR1H2
SCHEMBL8228982 0.92 CYP2C19 (0.68) CRHBPCRHR2CYP2C19CNR2NR1H2
SCHEMBL10054994 0.91 CRHBP (0.67) CRHBPCRHR2CYP2C19CNR2NR1H2
SCHEMBL4402952 0.89 CYP2C19 (0.52) CRHBPCRHR2CYP2C19CNR2NR1H2
SCHEMBL15079442 0.89 CYP2C19 (0.52) CRHBPCRHR2CYP2C19CNR2NR1H2
SCHEMBL642317 0.87 CRHBP (0.61) CRHBPCRHR2CYP2C19NR1H2NR1H3
SCHEMBL12679022 0.85 TAAR1 (0.63) CRHBPCRHR2NR1H2NR1H3HDAC3
Hydrochloric Acid SCHEMBL27388371 0.85 CRHBP (0.59) CRHBPCRHR2CYP2C19NR1H2NR1H3
SCHEMBL12679026 0.83 HRH3 (0.52) CRHBPCRHR2CYP2C19CNR2NR1H2
SCHEMBL156840 0.83 CRHBP (0.59) CRHBPCRHR2CNR2NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10472565-B2 Low temperature activator systems and methods for chemiluminescent reactions CYALUME TECHNOLOGIES, INC. (US) 2019-11-12 US claimed
EP-3004286-B1 BROAD TEMPERATURE PERFORMANCE CHEMILUMINESCENT SYSTEMS AND METHODS CYALUME TECH INC (US) 2019-08-28 EP claimed
EP-3004286-A1 BROAD TEMPERATURE PERFORMANCE CHEMILUMINESCENT SYSTEMS AND METHODS Cyalume Technologies, Inc (US) 2016-04-13 EP claimed
US-9115305-B2 Broad temperature performance chemiluminescent systems and methods CYALUME TECHNOLOGIES, INC. (US) 2015-08-25 US claimed
US-20140353559-A1 BROAD TEMPERATURE PERFORMANCE CHEMILUMINESCENT SYSTEMS AND METHODS Cyalume Technologies (US) 2014-12-04 US claimed
WO-2014194332-A1 BROAD TEMPERATURE PERFORMANCE CHEMILUMINESCENT SYSTEMS AND METHODS Cyalume Technologies (US) 2014-12-04 WO claimed
US-20140356975-A1 LOW TEMPERATURE ACTIVATOR SYSTEMS AND METHODS FOR CHEMILUMINESCENT REACTIONS Cyalume Technologies (US) 2014-12-04 US claimed
CN-115873420-B Core-shell dye, photosensitive resin composition, photosensitive resin film, color filter and CMOS image sensor 三星SDI株式会社 2024-10-18 CN disclosed
US-20230242496-A1 SOX11 INHIBITORS FOR TREATING MANTLE CELL LYMPHOMA ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) 2023-08-03 US disclosed
EP-3535374-B1 LEUCO POLYMERS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS PROCTER & GAMBLE (US) 2020-09-30 EP disclosed
US-20200095500-A1 LOW TEMPERATURE ACTIVATOR SYSTEMS AND METHODS FOR CHEMILUMINESCENT REACTIONS CYALUME TECHNOLOGIES, INC. 2020-03-26 US disclosed
US-10472565-B2 Low temperature activator systems and methods for chemiluminescent reactions CYALUME TECHNOLOGIES, INC. (US) 2019-11-12 US disclosed
EP-3004286-B1 BROAD TEMPERATURE PERFORMANCE CHEMILUMINESCENT SYSTEMS AND METHODS CYALUME TECH INC (US) 2019-08-28 EP disclosed
US-20140353559-A1 BROAD TEMPERATURE PERFORMANCE CHEMILUMINESCENT SYSTEMS AND METHODS Cyalume Technologies (US) 2014-12-04 US disclosed
US-20140356975-A1 LOW TEMPERATURE ACTIVATOR SYSTEMS AND METHODS FOR CHEMILUMINESCENT REACTIONS Cyalume Technologies (US) 2014-12-04 US disclosed
WO-2014194332-A1 BROAD TEMPERATURE PERFORMANCE CHEMILUMINESCENT SYSTEMS AND METHODS Cyalume Technologies (US) 2014-12-04 WO disclosed
US-20140353558-A1 MIXED CATALYST SYSTEMS AND METHODS FOR CHEMILUMINESCENT REACTIONS Cyalume Technologies (US) 2014-12-04 US disclosed
US-4528136-A Process for preparing 2-[bis(aryl)methyl]benzoic acids THE HILTON-DAVIS CHEMICAL CO. (US) 1985-07-09 US disclosed
US-4399291-A CONDENSATION OF A BENZALDEHYDE, AN ANILINE, AN AMINOBENZOIC ACID; OXIDATION STERLING DRUG INC. (US) 1983-08-16 US disclosed
EP-0082394-A2 A process for the production of aminophthalides and amino benzoic acids STERLING DRUG INC. (US) 1983-06-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230242496-A1 SOX11 INHIBITORS FOR TREATING MANTLE CELL LYMPHOMA BCL6, SOX18, BCL3 CRHBP 4043/4885CRHR2 4762/4885CYP2C19 4663/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.