Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | PPARA | Q07869 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | FABP2 | P12104 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pivalate SCHEMBL27380361 | 0.86 | TSHR (0.55) | TSHRPPARAMAPTKMT2ACYP1A2 | |
| Chlorobenzene SCHEMBL4418883 | 0.78 | TSHR (0.58) | TSHRPPARAMAPTKMT2ACYP1A2 | |
| Chlorobenzene SCHEMBL27741176 | 0.78 | TSHR (0.65) | TSHRMAPTKMT2ACYP1A2MEN1 | |
| Chlorobenzene SCHEMBL15241142 | 0.78 | TSHR (0.65) | TSHRMAPTKMT2ACYP1A2MEN1 | |
| Chlorobenzene SCHEMBL7973676 | 0.78 | TSHR (0.65) | TSHRPPARAMAPTKMT2ACYP1A2 | |
| Chlorobenzene SCHEMBL2830970 | 0.78 | TSHR (0.65) | TSHRMAPTKMT2ACYP1A2MEN1 | |
| Chlorobenzene SCHEMBL15240757 | 0.78 | TSHR (0.65) | TSHRMAPTKMT2ACYP1A2MEN1 | |
| Chlorobenzene SCHEMBL4166598 | 0.78 | TSHR (0.65) | TSHRMAPTKMT2ACYP1A2MEN1 | |
| Chlorobenzene SCHEMBL2533883 | 0.77 | TSHR (0.73) | TSHRMAPTKMT2ACYP1A2MEN1 | |
| Chlorobenzene SCHEMBL29172530 | 0.77 | TSHR (0.73) | TSHRMAPTKMT2ACYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4528286-A | Method of using certain aryl-mercapto-lower-alkanamides as antiseborrheic agents | HENKEL KOMMANDITGESELLSCHAFT (KGAA) (DE) | 1985-07-09 | — | — | US | disclosed |