SCHEMBL11001908

SCHEMBL11001908

CN(C)NC(=O)CCC(=O)O.CNN(C)C(=O)CCC(=O)O

nearest known ligand 0.71

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PHF8 Q9UPP1 9/20 0.71
KDM2A Q9Y2K7 9/20 0.71
KDM7A Q6ZMT4 2/20 0.71
KDM5C P41229 5/20 0.42
EGLN1 Q9GZT9 5/20 0.42
KDM4E B2RXH2 4/20 0.42
KDM6B O15054 3/20 0.38
FOLH1 Q04609 1/20 0.38
KDM4A O75164 7/20 0.34
KDM4C Q9H3R0 7/20 0.34
LMNA P02545 2/20 0.32
ALKBH5 Q6P6C2 1/20 0.32
SUCNR1 Q9BXA5 1/20 0.32
POLB P06746 1/20 0.32
SLC15A2 Q16348 1/20 0.31
KDM5A P29375 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10897803 0.87 PHF8 (0.54) PHF8KDM2AKDM7AKDM5CEGLN1
Succinic Acid SCHEMBL18497045 0.84 PHF8 (1.00) PHF8KDM2AKDM7AKDM5CEGLN1
SCHEMBL17047606 0.84 PHF8 (1.00) PHF8KDM2AKDM7AKDM5CEGLN1
Succinic Acid SCHEMBL18497046 0.84 PHF8 (1.00) PHF8KDM2AKDM7AKDM5CEGLN1
SCHEMBL50347 0.84 PHF8 (1.00) PHF8KDM2AKDM7AKDM5CEGLN1
SCHEMBL28264782 0.79 PHF8 (0.87) PHF8KDM2AKDM7AKDM5CEGLN1
SCHEMBL10897809 0.78 PHF8 (0.39) PHF8KDM2AKDM7ALMNA
Glycine SCHEMBL8159005 0.77 PHF8 (0.83) PHF8KDM2AKDM7AKDM5CEGLN1
SCHEMBL584428 0.76 PHF8 (0.80) PHF8KDM2AKDM7AKDM5CEGLN1
SCHEMBL11855433 0.75 SLC22A6 (0.48) PHF8KDM2AKDM7AKDM4AKDM4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4504303-A Derivatives of azoles having phytogrowth regulating activity MONTEDISON S.P.A. (IT) 1985-03-12 US disclosed