Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHF8 | Q9UPP1 | 8/20 | 1.00 |
| ▸ | KDM2A | Q9Y2K7 | 8/20 | 1.00 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 1.00 |
| ▸ | EGLN1 | Q9GZT9 | 6/20 | 0.50 |
| ▸ | KDM5C | P41229 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | KDM6B | O15054 | 3/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.45 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.45 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.42 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL18497046 | 1.00 | PHF8 (1.00) | PHF8KDM2AKDM7AEGLN1KDM5C | |
| SCHEMBL50347 | 1.00 | PHF8 (1.00) | PHF8KDM2AKDM7AEGLN1KDM5C | |
| SCHEMBL17047606 | 1.00 | PHF8 (1.00) | PHF8KDM2AKDM7AEGLN1KDM5C | |
| SCHEMBL28264782 | 0.93 | PHF8 (0.87) | PHF8KDM2AKDM7AEGLN1KDM5C | |
| Glycine SCHEMBL8159005 | 0.91 | PHF8 (0.83) | PHF8KDM2AKDM7AEGLN1KDM5C | |
| SCHEMBL584428 | 0.89 | PHF8 (0.80) | PHF8KDM2AKDM7AEGLN1KDM5C | |
| SCHEMBL11001908 | 0.84 | PHF8 (0.71) | PHF8KDM2AKDM7AEGLN1KDM5C | |
| Valine SCHEMBL17378163 | 0.82 | PHF8 (0.67) | PHF8KDM2AKDM7AEGLN1KDM5C | |
| SCHEMBL10428009 | 0.82 | PHF8 (0.67) | PHF8KDM2AKDM7AEGLN1KDM5C | |
| Hydrochloric Acid SCHEMBL10387188 | 0.80 | PHF8 (0.65) | PHF8KDM2AKDM7AEGLN1KDM5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12016283-B2 | Compositions and their use for pest control and to induce plant hormone and gene regulation for improved plant production and defense | BIODEL AG INC. (US) | 2024-06-25 | — | — | US | disclosed |
| US-20210337751-A1 | COMPOSITIONS AND THEIR USE FOR PEST CONTROL AND TO INDUCE PLANT HORMONE AND GENE REGULATION FOR IMPROVED PLANT PRODUCTION AND DEFENSE | BIODEL AG INC. | 2021-11-04 | — | — | US | disclosed |
| US-11083147-B2 | Compositions and their use for pest control and to induce plant hormone and gene regulation for improved plant production and defense | BIODEL AG INC. (US) | 2021-08-10 | — | — | US | disclosed |
| US-11076543-B2 | Compositions and their use for pest control and to induce plant hormone and gene regulation for improved plant production and defense | BIODEL AG INC. (US) | 2021-08-03 | — | — | US | disclosed |
| US-20200120888-A1 | COMPOSITIONS AND THEIR USE FOR PEST CONTROL AND TO INDUCE PLANT HORMONE AND GENE REGULATION FOR IMPROVED PLANT PRODUCTION AND DEFENSE | BIODEL AG INC. | 2020-04-23 | — | — | US | disclosed |
| US-20200120887-A1 | COMPOSITIONS AND THEIR USE FOR PEST CONTROL AND TO INDUCE PLANT HORMONE AND GENE REGULATION FOR IMPROVED PLANT PRODUCTION AND DEFENSE | BIODEL AG INC. | 2020-04-23 | — | — | US | disclosed |
| US-10542686-B2 | Compositions and their use for pest control and to induce plant hormone and gene regulation for improved plant production and defense | BEEM BIOLOGICS INC. (US) | 2020-01-28 | — | — | US | disclosed |
| EP-3334274-A1 | COMPOSITIONS AND THEIR USE FOR PEST CONTROL AND TO INDUCE PLANT HORMONE AND GENE REGULATION FOR IMPROVED PLANT PRODUCTION AND DEFENSE | Beem Biologics Inc. (US) | 2018-06-20 | — | — | EP | disclosed |
| US-20180139918-A1 | COMPOSITIONS AND THEIR USE FOR PEST CONTROL AND TO INDUCE PLANT HORMONE AND GENE REGULATION FOR IMPROVED PLANT PRODUCTION AND DEFENSE | BEEM BIOLOGICS INC. (US) | 2018-05-24 | — | — | US | disclosed |
| CN-108024519-A | For the composition and its application of control of insect and induction plant hormone and gene regulation to improve plant production with defend | 比姆生物制品有限公司 | 2018-05-11 | — | — | CN | disclosed |
| WO-2017027606-A1 | COMPOSITIONS AND THEIR USE FOR PEST CONTROL AND TO INDUCE PLANT HORMONE AND GENE REGULATION FOR IMPROVED PLANT PRODUCTION AND DEFENSE | BEEM BIOLOGICS INC. (US) | 2017-02-16 | — | — | WO | disclosed |