Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHF8 | Q9UPP1 | 5/20 | 0.80 |
| ▸ | KDM2A | Q9Y2K7 | 5/20 | 0.80 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | KDM5C | P41229 | 3/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.35 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL50347 | 0.89 | PHF8 (1.00) | PHF8KDM2AKDM7AKDM4EKDM5C | |
| Succinic Acid SCHEMBL18497045 | 0.89 | PHF8 (1.00) | PHF8KDM2AKDM7AKDM4EKDM5C | |
| SCHEMBL17047606 | 0.89 | PHF8 (1.00) | PHF8KDM2AKDM7AKDM4EKDM5C | |
| Succinic Acid SCHEMBL18497046 | 0.89 | PHF8 (1.00) | PHF8KDM2AKDM7AKDM4EKDM5C | |
| SCHEMBL3401157 | 0.87 | PHF8 (0.64) | PHF8KDM2AKDM7AKDM4EKDM5C | |
| SCHEMBL1792763 | 0.86 | — | — | |
| SCHEMBL10519966 | 0.86 | — | — | |
| SCHEMBL13545169 | 0.85 | KDM7A (0.61) | PHF8KDM2AKDM7AMEN1KMT2A | |
| SCHEMBL24293824 | 0.84 | — | — | |
| SCHEMBL8747962 | 0.84 | KDM7A (0.60) | PHF8KDM2AKDM7AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10072043-B2 | Inhibitors of protein tyrosine phosphatases | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2018-09-11 | — | — | US | claimed |
| US-20160176922-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | Indiana University Research and Technology Corpora tion (US) | 2016-06-23 | — | — | US | claimed |
| US-9217012-B2 | Inhibitors of protein tyrosine phosphatases | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2015-12-22 | — | — | US | claimed |
| US-20120108431-A1 | PLANT GROWTH REGULATOR ADDITIVE | TAMINCO, NAAMLOZE VENNOOTSCHAP (BE) | 2012-05-03 | — | — | US | claimed |
| US-20120088720-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATI (US) | 2012-04-12 | — | — | US | claimed |
| EP-2416653-A2 | PLANT GROWTH REGULATOR ADDITIVE | Taminco, Naamloze Vennootschap (BE) | 2012-02-15 | — | — | EP | claimed |
| WO-2010116259-A2 | PLANT GROWTH REGULATOR ADDITIVE | TAMINCO, NAAMLOZE VENNOOTSCHAP (BE) | 2010-10-14 | — | — | WO | claimed |
| WO-2010118241-A2 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION (US) | 2010-10-14 | — | — | WO | claimed |
| EP-0388109-B1 | Potato Production | KOREA INST SCI & TECH (KR) | 1995-03-15 | — | — | EP | claimed |
| US-4061490-A | 2-BENZIMIDOYL-3-HYDROXY-1,4-NAPHTHOQUINONE | SHIONOGI & CO., LTD. (JA) | 1977-12-06 | — | — | US | claimed |
| US-12551555-B2 | Compositions and methods for potentiating immune activity | KUMQUAT BIOSCIENCES INC. (US) | 2026-02-17 | — | — | US | disclosed |
| EP-4661890-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | Purdue Research Foundation (US) | 2025-12-17 | — | — | EP | disclosed |
| WO-2024167565-A1 | PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS | PURDUE RESEARCH FOUNDATION (US) | 2024-08-15 | — | — | WO | disclosed |
| WO-2024122103-A1 | ETCHING SOLUTION COMPOSITION | ラサ工業株式会社 | 2024-06-13 | — | — | WO | disclosed |
| US-20230044323-A1 | COMPOSITIONS AND METHODS FOR POTENTIATING IMMUNE ACTIVITY | KUMQUAT BIOSCIENCES INC. | 2023-02-09 | — | — | US | disclosed |
| US-4051142-A | PLANT GROWTH REGULATORS | ROHM AND HAAS COMPANY (US) | 1977-09-27 | — | — | US | disclosed |
| US-4038065-A | 1-ALKYLPYRID-2-ONE | ROHM AND HAAS COMPANY (US) | 1977-07-26 | — | — | US | disclosed |
| US-4009021-A | Imidazole plant growth regulators | ROHM AND HAAS COMPANY (US) | 1977-02-22 | — | — | US | disclosed |
| US-3941800-A | PLANT GROWTH REGULATOR | BAYER AKTIENGESELLSCHAFT (DT) | 1976-03-02 | — | — | US | disclosed |
| US-3932448-A | FUNGICIDES, MITICIDES | E. I. DU PONT DE NEMOURS & COMPANY (US) | 1976-01-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10072043-B2 | Inhibitors of protein tyrosine phosphatases | PTPRCAP, PTPRF, PTPRS | PHF8 1423/4885KDM2A 2051/4885KDM7A 1986/4885 |
| US-12551555-B2 | Compositions and methods for potentiating immune activity | PTPRCAP, PTPN2, PTPRC | PHF8 3725/4885KDM2A 1318/4885KDM7A 3350/4885 |
| US-20160176922-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | PTPRCAP, PTPRF, PTPRS | PHF8 1423/4885KDM2A 2051/4885KDM7A 1986/4885 |
| US-20230044323-A1 | COMPOSITIONS AND METHODS FOR POTENTIATING IMMUNE ACTIVITY | NFATC1, MYD88, ICOS | PHF8 3222/4885KDM2A 2722/4885KDM7A 2621/4885 |
| US-20120088720-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES | PTPRCAP, PTPRF, PTPRS | PHF8 1423/4885KDM2A 2051/4885KDM7A 1986/4885 |
| US-20120108431-A1 | PLANT GROWTH REGULATOR ADDITIVE | MYB, ING2, AGXT | PHF8 887/4885KDM2A 906/4885KDM7A 1570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.