Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 4/20 | 0.36 |
| ▸ | PKM | P14618 | 3/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11001441 | 0.92 | PKM (0.44) | GRM5L3MBTL1TDP1POLBKMT2A | |
| SCHEMBL10997683 | 0.91 | HTT (0.47) | GRM5POLBKMT2AALDH1A1MAPT | |
| SCHEMBL10997983 | 0.91 | HTT (0.46) | GRM5L3MBTL1TDP1POLBKMT2A | |
| SCHEMBL11002540 | 0.89 | HTT (0.41) | L3MBTL1TDP1POLBALDH1A1KDM4E | |
| SCHEMBL11005519 | 0.86 | PKM (0.46) | L3MBTL1POLBALDH1A1KDM4EMAPT | |
| SCHEMBL11003901 | 0.84 | HTT (0.49) | TDP1POLBALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11004662 | 0.84 | HTT (0.48) | L3MBTL1TDP1POLBALDH1A1KDM4E | |
| SCHEMBL11001673 | 0.84 | GRM5 (0.38) | GRM5POLBALDH1A1KDM4EMAPT | |
| SCHEMBL11002155 | 0.84 | HTT (0.42) | GRM5POLBKMT2AALDH1A1MAPT | |
| SCHEMBL10997874 | 0.83 | KDM4E (0.44) | GRM5NAMPTPOLBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4537962-A | ANTIULCER, ANTISECRETORY AGENTS | FARMITALIA CARLO ERBA, S.P.A. (IT) | 1985-08-27 | — | — | US | disclosed |