Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 5/20 | 0.46 |
| ▸ | PKM | P14618 | 5/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11001441 | 0.92 | PKM (0.44) | HTTPKMGFERMAPTKDM4E | |
| SCHEMBL11001990 | 0.91 | GRM5 (0.38) | HTTPKMMAPTKDM4EALDH1A1 | |
| SCHEMBL10997683 | 0.91 | HTT (0.47) | HTTPKMGFERMAPTALDH1A1 | |
| SCHEMBL11001673 | 0.87 | GRM5 (0.38) | HTTPKMGFERMAPTKDM4E | |
| SCHEMBL11004662 | 0.84 | HTT (0.48) | HTTPKMGFERMAPTKDM4E | |
| SCHEMBL11002155 | 0.84 | HTT (0.42) | HTTPKMGFERMAPTALDH1A1 | |
| SCHEMBL11004418 | 0.83 | ALDH1A1 (0.43) | MAPTKDM4EALDH1A1GRM5POLB | |
| SCHEMBL10998757 | 0.82 | GRM5 (0.41) | HTTPKMMAPTKDM4EALDH1A1 | |
| SCHEMBL11000459 | 0.81 | GRM5 (0.44) | MAPTKDM4EALDH1A1LMNAMAPK1 | |
| SCHEMBL11002949 | 0.80 | GRM5 (0.44) | MAPTKDM4EALDH1A1MAPK1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4537962-A | ANTIULCER, ANTISECRETORY AGENTS | FARMITALIA CARLO ERBA, S.P.A. (IT) | 1985-08-27 | — | — | US | disclosed |