Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.32 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11002008 | 1.00 | MAPT (0.38) | MAPTTRIM24TRIM33ALDH1A1CRBN | |
| SCHEMBL2046509 | 0.80 | TRIM24 (0.38) | MAPTTRIM24TRIM33ALDH1A1CRBN | |
| SCHEMBL2048808 | 0.80 | TRIM24 (0.38) | MAPTTRIM24TRIM33ALDH1A1CRBN | |
| SCHEMBL2046507 | 0.80 | TRIM24 (0.38) | MAPTTRIM24TRIM33ALDH1A1CRBN | |
| SCHEMBL19745458 | 0.79 | TRIM24 (0.50) | MAPTTRIM24TRIM33ALDH1A1CRBN | |
| SCHEMBL21925246 | 0.77 | TRIM24 (0.53) | MAPTTRIM24TRIM33ALDH1A1CRBN | |
| SCHEMBL21925266 | 0.77 | TRIM24 (0.53) | MAPTTRIM24TRIM33ALDH1A1CRBN | |
| SCHEMBL22320959 | 0.77 | TRIM24 (0.53) | MAPTTRIM24TRIM33ALDH1A1CRBN | |
| SCHEMBL1655400 | 0.77 | TRIM24 (0.53) | MAPTTRIM24TRIM33ALDH1A1CRBN | |
| SCHEMBL727114 | 0.77 | TRIM24 (0.53) | MAPTTRIM24TRIM33ALDH1A1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4510330-A | Process for the preparation of δ-ethylenic carbonyl compounds | RHONE-POULENC SANTE (FR) | 1985-04-09 | — | — | US | disclosed |