SCHEMBL19745458

SCHEMBL19745458

CC1CC(=O)CCCCC(=O)C1

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TRIM24 O15164 2/20 0.50
TRIM33 Q9UPN9 2/20 0.50
ALDH1A1 P00352 1/20 0.47
CRBN Q96SW2 1/20 0.43
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA4 P22748 1/20 0.40
KMT2A Q03164 1/20 0.39
THRB P10828 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.33
MAPT P10636 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21925246 0.97 TRIM24 (0.53) TRIM24TRIM33ALDH1A1CRBNCA1
SCHEMBL21925266 0.97 TRIM24 (0.53) TRIM24TRIM33ALDH1A1CRBNCA1
SCHEMBL1655400 0.97 TRIM24 (0.53) TRIM24TRIM33ALDH1A1CRBNCA1
SCHEMBL727114 0.97 TRIM24 (0.53) TRIM24TRIM33ALDH1A1CRBNCA1
SCHEMBL22320959 0.97 TRIM24 (0.53) TRIM24TRIM33ALDH1A1CRBNCA1
SCHEMBL1655628 0.97 TRIM24 (0.53) TRIM24TRIM33ALDH1A1CRBNCA1
SCHEMBL105656 0.87
SCHEMBL14066006 0.87
SCHEMBL2046507 0.86 TRIM24 (0.38) TRIM24TRIM33ALDH1A1CRBNCA1
SCHEMBL2046509 0.86 TRIM24 (0.38) TRIM24TRIM33ALDH1A1CRBNCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11840542-B2 Method for producing cyclic enol ether compound KAO CORPORATION (JP) 2023-12-12 US disclosed
US-10668446-B2 Flow-through reactors for the continuous quenching of peroxide mixtures and methods comprising the same P2 SCIENCE, INC. (US) 2020-06-02 US disclosed
US-10668446-B2 Flow-through reactors for the continuous quenching of peroxide mixtures and methods comprising the same P2 SCIENCE, INC. (US) 2020-06-02 US disclosed
EP-3472124-A1 FLOW-THROUGH REACTORS FOR THE CONTINUOUS QUENCHING OF PEROXIDE MIXTURES AND METHODS COMPRISING THE SAME P2 Science, Inc. (US) 2019-04-24 EP disclosed
US-20190091645-A1 FLOW-THROUGH REACTORS FOR THE CONTINUOUS QUENCHING OF PEROXIDE MIXTURES AND METHODS COMPRISING THE SAME P2 SCIENCE, INC. 2019-03-28 US disclosed
US-20190091645-A1 FLOW-THROUGH REACTORS FOR THE CONTINUOUS QUENCHING OF PEROXIDE MIXTURES AND METHODS COMPRISING THE SAME P2 SCIENCE, INC. 2019-03-28 US disclosed
WO-2017223220-A1 FLOW-THROUGH REACTORS FOR THE CONTINUOUS QUENCHING OF PEROXIDE MIXTURES AND METHODS COMPRISING THE SAME P2 SCIENCE, INC. (US) 2017-12-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11840542-B2 Method for producing cyclic enol ether compound ERG28, ADH1A, SQLE TRIM24 1205/4885TRIM33 3829/4885ALDH1A1 632/4885
US-10668446-B2 Flow-through reactors for the continuous quenching of peroxide mixtures and methods comprising the same GPX4, NOX5, NOX4 TRIM24 2770/4885TRIM33 1725/4885ALDH1A1 2884/4885
US-20190091645-A1 FLOW-THROUGH REACTORS FOR THE CONTINUOUS QUENCHING OF PEROXIDE MIXTURES AND METHODS COMPRISING THE SAME GPX4, NOX5, NOX4 TRIM24 2770/4885TRIM33 1725/4885ALDH1A1 2884/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.