Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.49 |
| ▸ | FEN1 | P39748 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10837512 | 0.81 | TSHR (0.46) | SMN1; SMN2TSHRCASP1ERCC5FEN1 | |
| SCHEMBL10516101 | 0.79 | GLA (0.59) | SMN1; SMN2TSHRCASP1ERCC5FEN1 | |
| SCHEMBL5536983 | 0.77 | SMN1; SMN2 (0.50) | SMN1; SMN2TSHRCASP1ERCC5FEN1 | |
| SCHEMBL1697496 | 0.76 | TSHR (0.69) | SMN1; SMN2TSHRCASP1ERCC5FEN1 | |
| SCHEMBL9077787 | 0.75 | EIF4A3 (0.30) | — | |
| SCHEMBL8065539 | 0.74 | SMN1; SMN2 (0.71) | SMN1; SMN2TSHRCASP1ERCC5FEN1 | |
| SCHEMBL8437669 | 0.74 | GPR17 (0.30) | — | |
| SCHEMBL8489008 | 0.72 | POLB (0.43) | SMN1; SMN2TSHRCASP1ERCC5FEN1 | |
| SCHEMBL8489006 | 0.72 | POLB (0.43) | SMN1; SMN2TSHRCASP1ERCC5FEN1 | |
| SCHEMBL11237622 | 0.72 | POLB (0.49) | SMN1; SMN2TSHRCASP1ERCC5FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4544658-A | FEED ADDITIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1985-10-01 | — | — | US | disclosed |