Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | CASP1 | P29466 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.59 |
| ▸ | FEN1 | P39748 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | FLT1 | P17948 | 2/20 | 0.47 |
| ▸ | FLT4 | P35916 | 2/20 | 0.47 |
| ▸ | KDR | P35968 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8065539 | 0.89 | SMN1; SMN2 (0.71) | TSHRCASP1SMN1; SMN2ERCC5FEN1 | |
| SCHEMBL7918742 | 0.84 | ALDH1A1 (0.54) | TSHRCASP1SMN1; SMN2ERCC5FEN1 | |
| SCHEMBL111279 | 0.82 | TSHR (1.00) | TSHRCASP1SMN1; SMN2ERCC5FEN1 | |
| SCHEMBL3133251 | 0.81 | SMN1; SMN2 (0.61) | TSHRCASP1SMN1; SMN2ERCC5FEN1 | |
| SCHEMBL10791990 | 0.81 | SMN1; SMN2 (0.61) | TSHRCASP1SMN1; SMN2ERCC5FEN1 | |
| SCHEMBL9749593 | 0.80 | CES1 (0.62) | TSHRCASP1SMN1; SMN2ERCC5FEN1 | |
| Hydrochloric Acid SCHEMBL9651764 | 0.80 | TSHR (0.95) | TSHRCASP1SMN1; SMN2ERCC5FEN1 | |
| SCHEMBL6233608 | 0.80 | TSHR (0.95) | TSHRCASP1SMN1; SMN2ERCC5FEN1 | |
| SCHEMBL28852873 | 0.80 | TSHR (0.95) | TSHRCASP1SMN1; SMN2ERCC5FEN1 | |
| Ammonia Solution, Strong SCHEMBL4373474 | 0.80 | TSHR (0.95) | TSHRCASP1SMN1; SMN2ERCC5FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109776488-B | Synthesis method of alpha-ketoamide compound with ortho-aldehyde group | 江南大学 | 2021-04-27 | — | — | CN | disclosed |
| US-20130109884-A1 | PROCESS FOR PRODUCING ALPHA-KETOCARBOXYLIC ACID | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-05-02 | — | — | US | disclosed |
| EP-2585427-A1 | PROCESS FOR PRODUCING ALPHA-KETOCARBOXYLIC ACID | Sumitomo Chemical Company Limited (JP) | 2013-05-01 | — | — | EP | disclosed |
| WO-2011162404-A1 | PROCESS FOR PRODUCING ALPHA-KETOCARBOXYLIC ACID | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109884-A1 | PROCESS FOR PRODUCING ALPHA-KETOCARBOXYLIC ACID | ALDH18A1, MCCC2, ALDH7A1 | TSHR 4683/4885CASP1 338/4885SMN1; SMN2 4535/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.