Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 19/20 | 0.48 |
| ▸ | CA2 | P00918 | 19/20 | 0.48 |
| ▸ | CA9 | Q16790 | 14/20 | 0.48 |
| ▸ | CA4 | P22748 | 12/20 | 0.48 |
| ▸ | CA7 | P43166 | 5/20 | 0.48 |
| ▸ | CA12 | O43570 | 9/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11000956 | 0.87 | CA1 (0.57) | CA1CA2CA9CA4CA7 | |
| SCHEMBL10999356 | 0.85 | MAPT (0.48) | CA1CA2CA9CA4CA7 | |
| SCHEMBL10996162 | 0.82 | LMNA (0.49) | CA1CA2CA9CA4CA7 | |
| SCHEMBL11000455 | 0.81 | PTGS1 (0.47) | CA1CA2CA9CA4CA7 | |
| SCHEMBL11003710 | 0.79 | TP53 (0.42) | — | |
| SCHEMBL10999213 | 0.79 | PPARG (0.55) | — | |
| SCHEMBL10999899 | 0.79 | CA1 (0.53) | CA1CA2CA9CA4CA7 | |
| SCHEMBL10997308 | 0.79 | CA1 (0.53) | CA1CA2CA9CA4CA7 | |
| SCHEMBL11001879 | 0.78 | CA1 (0.50) | CA1CA2CA9CA4CA7 | |
| SCHEMBL10997735 | 0.76 | CA2 (0.57) | CA1CA2CA9CA4CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4505921-A | Sulfonylurea compounds and their use in treating diabetes | ADIR, S.A.R.L. (FR) | 1985-03-19 | — | — | US | disclosed |