Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA7 | P43166 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19444459 | 0.79 | TYR (0.48) | TYRCA12CA1CA2CA7 | |
| SCHEMBL7458752 | 0.78 | TYR (0.47) | TYRCA12CA1CA2CA7 | |
| SCHEMBL9988674 | 0.78 | TYR (0.47) | TYRCA12CA1CA2CA7 | |
| SCHEMBL9006525 | 0.76 | TYR (0.48) | TYRCA12CA1CA2CA7 | |
| SCHEMBL11018237 | 0.76 | MEN1 (0.62) | TYRCA12CA1CA2CA7 | |
| SCHEMBL29429345 | 0.76 | TYR (0.55) | TYRCA12CA1CA2CA7 | |
| SCHEMBL490490 | 0.76 | TYR (0.55) | TYRCA12CA1CA2CA7 | |
| SCHEMBL19444291 | 0.74 | TYR (0.44) | TYRCA12CA1CA2CA7 | |
| SCHEMBL28880611 | 0.72 | TYR (0.55) | TYRCA12CA1CA2CA7 | |
| SCHEMBL27965885 | 0.72 | TYR (0.59) | TYRCA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4528286-A | Method of using certain aryl-mercapto-lower-alkanamides as antiseborrheic agents | HENKEL KOMMANDITGESELLSCHAFT (KGAA) (DE) | 1985-07-09 | — | — | US | disclosed |