Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28880611 | 0.81 | TYR (0.55) | TYRCA12CA1CA2CA7 | |
| SCHEMBL28642768 | 0.79 | TYR (0.52) | TYRESR1CES2 | |
| SCHEMBL22278955 | 0.77 | TYR (0.50) | TYRESR1CES2 | |
| SCHEMBL8577488 | 0.77 | TYR (0.50) | TYRESR1CES2 | |
| SCHEMBL11003304 | 0.76 | TYR (0.46) | TYRCES2ALOX5CA12ALDH1A1 | |
| SCHEMBL31546086 | 0.75 | TYR (0.59) | TYRCA12CA1CA2CA7 | |
| SCHEMBL51618 | 0.75 | TYR (0.70) | TYRESR1CA12CA1CA2 | |
| SCHEMBL383417 | 0.75 | LMNA (0.64) | TYRCA12CA1CA2TSHR | |
| SCHEMBL28826562 | 0.75 | TYR (0.48) | TYRESR1CES2 | |
| SCHEMBL16449409 | 0.75 | ESR1 (0.50) | TYRESR1CES2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623341-B1 | Use of 4-thioresorcin derivatives in skin whitening cosmetic or dermopharmaceutical compositions | OREAL (FR) | 1996-10-16 | — | — | EP | claimed |
| EP-0623341-A1 | Use of 4-thioresorcin derivatives in skin whitening cosmetic or dermopharmaceutical compositions | L'OREAL (FR) | 1994-11-09 | — | — | EP | disclosed |