SCHEMBL490490

SCHEMBL490490

CC(C(=O)O)c1ccc(O)cc1O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 1/20 0.55
PTGS2 P35354 2/20 0.47
PTGS1 P23219 1/20 0.47
CA12 O43570 4/20 0.45
CA1 P00915 4/20 0.45
CA2 P00918 4/20 0.45
CA7 P43166 4/20 0.45
CA9 Q16790 4/20 0.45
CA14 Q9ULX7 4/20 0.45
ALDH1A1 P00352 1/20 0.45
TSHR P16473 1/20 0.45
CES2 O00748 1/20 0.42
ALOX5 P09917 1/20 0.41
CYP3A4 P08684 3/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
CYP1A2 P05177 1/20 0.41
MAPT P10636 1/20 0.41
PPARG P37231 1/20 0.41
APP P05067 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29429345 1.00 TYR (0.55) TYRPTGS2PTGS1CA12CA1
SCHEMBL27536509 0.86 TYR (0.52) TYRCA12CA1CA2CA7
SCHEMBL490883 0.84 PTGS2 (0.60) TYRPTGS2PTGS1CA12CA1
SCHEMBL23276484 0.82 TYR (0.49) TYRCA12CA1CA2CA7
SCHEMBL28238190 0.82 TRPA1 (0.62) PTGS2PTGS1ALDH1A1MEN1KMT2A
SCHEMBL28745580 0.82 PTGS1 (0.42) TYRPTGS2PTGS1CYP3A4MEN1
SCHEMBL19028073 0.81 PTGS2 (0.45) TYRPTGS2PTGS1TSHRALOX5
SCHEMBL27678542 0.81 PTGS2 (0.45) PTGS2PTGS1CA9CA14TSHR
SCHEMBL27697380 0.81 PTGS2 (0.45) PTGS2PTGS1CA1CA2ALDH1A1
SCHEMBL9437482 0.81 CYP3A4 (0.42) TYRPTGS2PTGS1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5631038-A COMPOUNDS (TASTANDS) TO REDUCE OR ELIMINATE A BITTER OR METALLIC TASTE ARE ADDED TO FOODS CONTAINING SODIUM CHLORIDE BIORESEARCH, INC. (US) 1997-05-20 US claimed
US-5631294-A PHENOXY- OR PHENYL-ALKANOIC ACIDS BIORESEARCH, INC. (US) 1997-05-20 US claimed
EP-0661932-A4 SPECIFIC EATABLE TASTE MODIFIERS. BIORESEARCH INC (US) 1996-06-05 EP claimed
EP-0661932-A1 SPECIFIC EATABLE TASTE MODIFIERS BIORESEARCH, INC. (US) 1995-07-12 EP claimed
EP-0514467-B1 COMPOSITIONS AND METHODS FOR INHIBITING BROWNING IN FOODS OPTA FOOD INGREDIENTS INC (US) 1994-08-10 EP claimed
WO-1993010677-A1 SPECIFIC EATABLE TASTE MODIFIERS BIORESEARCH, INC. (US) 1993-06-10 WO claimed
WO-1991011119-A1 COMPOSITIONS AND METHODS FOR INHIBITING BROWNING IN FOODS OPTA FOOD INGREDIENTS, INC. (US) 1991-08-08 WO claimed
US-20250064703-A1 COMPOSITION COMPRISING SOLUBILIZED POLYPHENOL OREAL (FR) 2025-02-27 US disclosed
EP-4452205-A1 COMPOSITION COMPRISING SOLUBILIZED POLYPHENOL L'OREAL (FR) 2024-10-30 EP disclosed
EP-4337159-A1 COMPOSITION COMPRISING SKIN CARE ACTIVE INGREDIENT AND TWO POLYGLYCERYL FATTY ACID ESTERS L'OREAL (FR) 2024-03-20 EP disclosed
WO-2024014310-A1 COMPOSITION COMPRISING SKIN CARE ACTIVE INGREDIENT OR CELLULOSE COMPOUND L'OREAL (FR) 2024-01-18 WO disclosed
US-20230398047-A1 COMPOSITION COMPRISING SKIN CARE ACTIVE INGREDIENT AND TWO POLYGLYCERYL FATTY ACID ESTERS L'OREAL (FR) 2023-12-14 US disclosed
CN-116528820-A Composition comprising skin care active and two polyglycerin fatty acid esters 莱雅公司 2023-08-01 CN disclosed
EP-0661932-A1 SPECIFIC EATABLE TASTE MODIFIERS BIORESEARCH, INC. (US) 1995-07-12 EP disclosed
EP-0514467-B1 COMPOSITIONS AND METHODS FOR INHIBITING BROWNING IN FOODS OPTA FOOD INGREDIENTS INC (US) 1994-08-10 EP disclosed
US-5304679-A Using an aromatic oxyamide OPTA FOOD INGREDIENTS, INC. (US) 1994-04-19 US disclosed
US-5227487-A Phthalein dye derivatives, fluorescent dyes MOLECULAR PROBES, INC. (US) 1993-07-13 US disclosed
WO-1993010677-A1 SPECIFIC EATABLE TASTE MODIFIERS BIORESEARCH, INC. (US) 1993-06-10 WO disclosed
US-5059438-A COMPOSITIONS AND METHODS FOR INHIBITING BROWNING IN FOODS USING RESORCINOL DERIVATIVES ENZYTECH, INC. (US) 1991-10-22 US disclosed
WO-1991011119-A1 COMPOSITIONS AND METHODS FOR INHIBITING BROWNING IN FOODS OPTA FOOD INGREDIENTS, INC. (US) 1991-08-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230398047-A1 COMPOSITION COMPRISING SKIN CARE ACTIVE INGREDIENT AND TWO POLYGLYCERYL FATTY ACID ESTERS ELOVL5, ELOVL3, LIPA TYR 1632/4885PTGS2 1104/4885PTGS1 1141/4885
US-20250064703-A1 COMPOSITION COMPRISING SOLUBILIZED POLYPHENOL PROC, GANC, LGALS1 TYR 79/4885PTGS2 1787/4885PTGS1 1211/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.