Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 2/20 | 0.40 |
| ▸ | USP8 | P40818 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KHK | P50053 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.30 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10990688 | 0.84 | USP8 (0.39) | GLP1RUSP8ALDH1A1KDM4ELMNA | |
| SCHEMBL29987465 | 0.75 | ALDH1A1 (0.47) | USP8ALDH1A1KDM4EGAAKHK | |
| SCHEMBL10087543 | 0.75 | ALDH1A1 (0.47) | USP8ALDH1A1KDM4EGAAKHK | |
| SCHEMBL3607648 | 0.73 | KDM4E (0.44) | USP8ALDH1A1KDM4EGAALMNA | |
| SCHEMBL11117158 | 0.72 | ALDH1A1 (0.46) | USP8ALDH1A1KDM4EGAALMNA | |
| SCHEMBL10989408 | 0.70 | GLP1R (0.41) | GLP1R | |
| SCHEMBL10997715 | 0.70 | USP8 (0.35) | USP8ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL9640585 | 0.69 | ALDH1A1 (0.43) | GLP1RALDH1A1KDM4EGAALMNA | |
| SCHEMBL8200210 | 0.69 | ALDH1A1 (0.45) | USP8ALDH1A1KDM4EGAAKHK | |
| SCHEMBL11000333 | 0.68 | KDM4E (0.40) | USP8ALDH1A1KDM4EGAAKHK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4518599-A | FUNGICIDES, BACTERICIDES FOR INDUSTRY, AGRICULTURE VETERINARY MEDICINE | MERCK & CO., INC. (US) | 1985-05-21 | — | — | US | disclosed |