Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 7/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 7/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | USP7 | Q93009 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11001194 | 0.78 | PDGFRB (0.42) | ALDH1A1MAPTKDM4ETHRBL3MBTL1 | |
| SCHEMBL11000458 | 0.78 | PDGFRB (0.45) | ALDH1A1MAPTKDM4ETHRBL3MBTL1 | |
| SCHEMBL11447916 | 0.76 | MKNK1 (0.50) | ALDH1A1MAPTKDM4ETHRBL3MBTL1 | |
| SCHEMBL10997600 | 0.72 | MEN1 (0.41) | ALDH1A1MAPTKDM4ETHRBL3MBTL1 | |
| SCHEMBL10997645 | 0.71 | MAPT (0.44) | ALDH1A1MAPTKDM4ETHRBL3MBTL1 | |
| SCHEMBL10997700 | 0.71 | AURKB (0.53) | ALDH1A1MAPTKDM4ETHRBMEN1 | |
| SCHEMBL23346571 | 0.70 | PDGFRB (0.50) | ALDH1A1MAPTKDM4ETHRBL3MBTL1 | |
| SCHEMBL18074847 | 0.70 | PTGS2 (0.52) | ALDH1A1MAPTTHRBMEN1KMT2A | |
| SCHEMBL10263741 | 0.70 | TDP1 (0.42) | ALDH1A1MAPTKDM4EL3MBTL1MEN1 | |
| SCHEMBL13575374 | 0.69 | ALDH1A1 (0.41) | ALDH1A1MAPTKDM4ETHRBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4514400-A | Cardiotonic 5-heteroaryl-pyridone | WILLIAM H. RORER, INC. (US) | 1985-04-30 | — | — | US | disclosed |