SCHEMBL11004342

SCHEMBL11004342

O=C1[N]C(=O)C(Cl)=CN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2046609 0.74
SCHEMBL11200820 0.70
SCHEMBL8723031 0.66
SCHEMBL545785 0.65 HKDC1 (0.33)
SCHEMBL546397 0.61 LMNA (0.34)
SCHEMBL14932121 0.52
SCHEMBL440393 0.50
SCHEMBL7215897 0.49
SCHEMBL1413188 0.49 AHR (0.45)
SCHEMBL13407 0.47

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11597745-B2 β-modified phosphoric acid compound precursor, β-modified phosphoric acid compound, reaction inhibitor and medicine containing the same, and method for inhibiting reaction JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2023-03-07 US claimed
US-8076310-B2 Phosphonate nucleosides useful as active ingredients in pharmaceutical compositions for the treatment of viral infections, and intermediates for their production K.U.LEUVEN RESEARCH & DEVELOPMENT (BE) 2011-12-13 US claimed
US-11597745-B2 β-modified phosphoric acid compound precursor, β-modified phosphoric acid compound, reaction inhibitor and medicine containing the same, and method for inhibiting reaction JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2023-03-07 US disclosed
US-4558047-A ANTITUMOR AGENTS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1985-12-10 US disclosed
EP-0123473-A2 Morpholine derivatives, processes for the preparation thereof, the use thereof and pharmaceutical compositions containing them FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1984-10-31 EP disclosed