SCHEMBL17299366

SCHEMBL17299366

CC(=O)CNC(=O)c1ccc(C(=O)NCC(=O)O)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.67
MAPT P10636 1/20 0.67
HIF1A Q16665 1/20 0.67
SLC22A6 Q4U2R8 1/20 0.67
SLC22A8 Q8TCC7 1/20 0.67
SOST Q9BQB4 1/20 0.59
CA1 P00915 3/20 0.59
CA2 P00918 3/20 0.59
ATM Q13315 1/20 0.56
CA9 Q16790 1/20 0.53
MAPK1 P28482 2/20 0.50
PTPRC P08575 2/20 0.49
CTSL P07711 1/20 0.49
PTPN13 Q12923 1/20 0.49
POLB P06746 3/20 0.47
KMT2A Q03164 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
ITGB3 P05106 1/20 0.47
ITGA2B P08514 1/20 0.47
LMNA P02545 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13203130 0.92 KDM4E (0.53) KDM4EMAPTHIF1ASLC22A6SLC22A8
SCHEMBL11107537 0.89 KDM4E (0.80) KDM4EMAPTHIF1ASLC22A6SLC22A8
SCHEMBL618128 0.86 GAA (0.63) MAPTCA1CA9POLBLMNA
SCHEMBL13202996 0.86 RAB9A (0.49) KDM4EMAPTHIF1ASLC22A6SLC22A8
SCHEMBL5436981 0.84 TDP1 (0.60) MAPTPOLBKMT2ATDP1LMNA
SCHEMBL1285723 0.84 KDM4E (0.67) KDM4EMAPTHIF1ASLC22A6SLC22A8
SCHEMBL24224263 0.83 KDM4E (0.71) KDM4EMAPTHIF1ASLC22A6SLC22A8
SCHEMBL28968620 0.83 RAB9A (0.59) MAPTHIF1APOLBKMT2ALMNA
SCHEMBL13113151 0.82 MAPT (0.70) KDM4EMAPTHIF1ASLC22A6SLC22A8
SCHEMBL25316335 0.82 OGG1 (0.57) POLBKMT2ALMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9422398-B2 Copolymer, and method for preparing a monomer used to form the copolymer INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2016-08-23 US disclosed
US-20150344414-A1 COPOLYMER, AND METHOD FOR PREPARING A MONOMER USED TO FORM THE COPOLYMER INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2015-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150344414-A1 COPOLYMER, AND METHOD FOR PREPARING A MONOMER USED TO FORM THE COPOLYMER CCNH, PAM, POLH KDM4E 2889/4885MAPT 2535/4885HIF1A 189/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.