Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.37 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10370613 | 0.89 | SLC6A4 (0.38) | MCHR1SLC6A4SIGMAR1DRD2HRH3 | |
| SCHEMBL10370342 | 0.87 | ESR1 (0.39) | MCHR1MCHR2SLC6A4HRH3DRD3 | |
| SCHEMBL10368600 | 0.87 | TMEM97 (0.43) | HRH3KDM4CACHEMAOB | |
| SCHEMBL10368866 | 0.85 | TMEM97 (0.44) | HRH3KDM4CACHEMAOB | |
| SCHEMBL11008259 | 0.85 | TMEM97 (0.44) | HRH3KDM4CACHEMAOB | |
| SCHEMBL10369087 | 0.84 | HRH4 (0.44) | TDP1SLC6A4SIGMAR1DRD2HRH3 | |
| SCHEMBL10370645 | 0.83 | MAPT (0.50) | — | |
| SCHEMBL10831393 | 0.83 | KCNA3 (0.42) | MCHR1MCHR2SIGMAR1DRD2DRD3 | |
| SCHEMBL10368940 | 0.82 | HRH3 (0.46) | HRH3ACHEMAOB | |
| SCHEMBL10368895 | 0.79 | CNR2 (0.36) | MCHR1MCHR2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4533731-A | ANTIINFLAMMATORY AGENTS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1985-08-06 | — | — | US | disclosed |
| EP-0090972-A2 | Indazole derivatives | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1983-10-12 | — | — | EP | disclosed |