Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KLK7 | P49862 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | IDE | P14735 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10368600 | 0.89 | TMEM97 (0.43) | LMNA | |
| SCHEMBL11008259 | 0.88 | TMEM97 (0.44) | LMNA | |
| SCHEMBL10368866 | 0.88 | TMEM97 (0.44) | LMNA | |
| SCHEMBL10369087 | 0.86 | HRH4 (0.44) | MAPTTP53MAPK1KDM4ETSHR | |
| SCHEMBL10369107 | 0.85 | CNR2 (0.43) | KDM4EALDH1A1LMNAPOLB | |
| SCHEMBL11217081 | 0.85 | MAPT (0.50) | MAPTHTTTP53MAPK1ATM | |
| SCHEMBL10370613 | 0.84 | SLC6A4 (0.38) | MAPK1KDM4EALDH1A1LMNA | |
| SCHEMBL10368940 | 0.84 | HRH3 (0.46) | — | |
| SCHEMBL11005140 | 0.83 | TDP1 (0.40) | — | |
| SCHEMBL10369201 | 0.82 | HTR7 (0.47) | MAPTKDM4ETSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0090972-B1 | INDAZOLE DERIVATIVES | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1990-05-30 | — | — | EP | disclosed |
| US-4751302-A | ANTIINFLAMMATORY, ANTIULCER AGENTS, ANALGESICS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1988-06-14 | — | — | US | disclosed |
| US-4533731-A | ANTIINFLAMMATORY AGENTS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1985-08-06 | — | — | US | disclosed |
| EP-0090972-A2 | Indazole derivatives | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1983-10-12 | — | — | EP | disclosed |