Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.50 |
| ▸ | PPARD | Q03181 | 2/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10998671 | 0.91 | KCNH2 (0.51) | MAOBPPARAPPARGKMT2AMEN1 | |
| SCHEMBL11004834 | 0.89 | FFAR1 (0.50) | MAOBPPARAPPARGKMT2AMEN1 | |
| SCHEMBL11003085 | 0.89 | MAOB (0.50) | MAOBPPARDPPARAGPR84PPARG | |
| SCHEMBL11005065 | 0.88 | KMT2A (0.50) | MAOBKMT2AMEN1FFAR1ATM | |
| SCHEMBL5391064 | 0.83 | FFAR1 (0.67) | PPARGFFAR1NPC1RAB9ALTA4H | |
| SCHEMBL18636795 | 0.81 | KCNH2 (0.56) | MAOBPPARDPPARAKMT2AFFAR1 | |
| SCHEMBL5586552 | 0.81 | NPC1 (0.68) | MAOBPPARDPPARAGPR84PPARG | |
| SCHEMBL14586644 | 0.81 | DRD2 (0.60) | MAOBPPARDPPARAGPR84PPARG | |
| SCHEMBL10981393 | 0.81 | DRD2 (0.56) | MAOBPPARDPPARAGPR84PPARG | |
| SCHEMBL21331850 | 0.81 | GPR84 (0.61) | MAOBPPARDPPARAGPR84PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4556715-A | ANTILIPEMIC AGENTS | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1985-12-03 | — | — | US | disclosed |