Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.50 |
| ▸ | PPARD | Q03181 | 2/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11003782 | 0.89 | KMT2A (0.51) | MAOBPPARAHRH3PPARGKMT2A | |
| SCHEMBL11005147 | 0.89 | MAOB (0.50) | MAOBPPARDPPARAGPR84HRH3 | |
| SCHEMBL10981393 | 0.85 | DRD2 (0.56) | MAOBPPARDPPARAGPR84PPARG | |
| SCHEMBL966309 | 0.85 | MAOB (0.69) | MAOBHRH3KMT2AMAOAAPP | |
| SCHEMBL6658231 | 0.84 | HRH3 (0.59) | PPARAHRH3KMT2AMEN1FFAR1 | |
| SCHEMBL5175258 | 0.83 | FFAR1 (0.67) | HRH3PPARGFFAR1NPC1RAB9A | |
| SCHEMBL2773286 | 0.82 | LTA4H (0.49) | MAOBPPARAPPARGFFAR1MAOA | |
| SCHEMBL11003805 | 0.82 | LMNA (0.51) | MAOBPPARAHRH3PPARGKMT2A | |
| SCHEMBL10334718 | 0.82 | ALDH1A1 (0.58) | PPARAHRH3KMT2AMEN1FFAR1 | |
| SCHEMBL77492 | 0.82 | CA2 (0.59) | MAOBTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4556715-A | ANTILIPEMIC AGENTS | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1985-12-03 | — | — | US | disclosed |