Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 6/20 | 0.56 |
| ▸ | ATP4B | P51164 | 6/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.42 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2189557 | 0.83 | ATP4A (0.66) | ATP4AATP4BMAPK1MEN1CYP1A2 | |
| SCHEMBL10531597 | 0.78 | ATP4A (0.69) | ATP4AATP4BMAPK1MEN1CYP1A2 | |
| SCHEMBL10864200 | 0.76 | CYP3A4 (0.40) | ATP4AATP4BMAPK1MEN1CYP1A2 | |
| SCHEMBL11007608 | 0.76 | ATP4A (0.71) | ATP4AATP4BMAPK1MEN1CYP1A2 | |
| SCHEMBL11007610 | 0.76 | ATP4A (0.71) | ATP4AATP4BMAPK1MEN1CYP1A2 | |
| Hydrochloric Acid SCHEMBL9748976 | 0.76 | CYP3A4 (0.40) | ATP4AATP4BMAPK1MEN1CYP1A2 | |
| SCHEMBL14767520 | 0.75 | PI4KB (0.58) | ATP4AATP4BMAPK8ADORA3PI4KB | |
| SCHEMBL10960061 | 0.74 | ATP4A (0.49) | ATP4AATP4BMAPK1MEN1CYP1A2 | |
| SCHEMBL11101512 | 0.74 | ATP4A (0.46) | ATP4AATP4BMAPK1MEN1CYP1A2 | |
| SCHEMBL8239615 | 0.74 | ADORA3 (0.56) | MAPK8ADORA3HTTTTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4507294-A | TREATMENT OF PEPTIC ULCERS | SCHERING CORP. (US) | 1985-03-26 | — | — | US | disclosed |