Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GALR2 | O43603 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | CCR6 | P51684 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | MAX | P61244 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | PELP1 | Q8IZL8 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527822 | 0.84 | NPSR1 (0.45) | ALDH1A1NPSR1POLBSMN1; SMN2GALR2 | |
| SCHEMBL11005202 | 0.82 | ALDH1A1 (0.44) | ALDH1A1NPSR1POLBSMN1; SMN2GALR2 | |
| SCHEMBL1646147 | 0.82 | MAPT (0.48) | ALDH1A1NPSR1POLBSMN1; SMN2GALR2 | |
| SCHEMBL11003186 | 0.79 | KMT2A (0.53) | ALDH1A1NPSR1POLBSMN1; SMN2KMT2A | |
| SCHEMBL23389131 | 0.79 | NPSR1 (0.45) | ALDH1A1NPSR1POLBSMN1; SMN2GALR2 | |
| SCHEMBL1425030 | 0.78 | MAPT (0.55) | ALDH1A1NPSR1POLBSMN1; SMN2GALR2 | |
| SCHEMBL11005161 | 0.78 | NPSR1 (0.44) | ALDH1A1NPSR1POLBSMN1; SMN2GALR2 | |
| SCHEMBL9232481 | 0.77 | MAPT (0.54) | ALDH1A1NPSR1POLBSMN1; SMN2GALR2 | |
| SCHEMBL4652737 | 0.77 | MAPT (0.54) | ALDH1A1NPSR1POLBSMN1; SMN2GALR2 | |
| SCHEMBL9527341 | 0.77 | LMNA (0.48) | ALDH1A1NPSR1POLBSMN1; SMN2GALR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4555518-A | ANTIULCER AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1985-11-26 | — | — | US | disclosed |