Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | GALR2 | O43603 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11002997 | 0.84 | ALDH1A1 (0.46) | SNCAALDH1A1CYP2D6CYP2C9CASP1 | |
| SCHEMBL8460305 | 0.78 | SNCA (0.48) | SNCAALDH1A1CYP2D6CYP2C9CASP1 | |
| SCHEMBL25624229 | 0.73 | CYP1A2 (0.53) | ALDH1A1HSD17B10CYP3A4CYP1A2GALR2 | |
| SCHEMBL11002602 | 0.73 | TSHR (0.42) | ALDH1A1CYP3A4LMNAMAPTL3MBTL1 | |
| SCHEMBL26977016 | 0.71 | SNCA (0.47) | SNCAALDH1A1CYP3A4CYP1A2ALOX15 | |
| SCHEMBL23257600 | 0.69 | MAPT (0.46) | ALDH1A1HSD17B10CYP3A4CYP1A2ALOX15 | |
| SCHEMBL31039440 | 0.69 | MAPT (0.46) | ALDH1A1HSD17B10CYP3A4CYP1A2ALOX15 | |
| SCHEMBL9978515 | 0.69 | ALDH1A1 (0.41) | ALDH1A1CYP3A4POLBMAPTGAA | |
| SCHEMBL2144114 | 0.69 | ALDH1A1 (0.49) | ALDH1A1CYP2D6HSD17B10CYP3A4ALOX15 | |
| SCHEMBL30423974 | 0.69 | ALDH1A1 (0.49) | ALDH1A1CYP2D6HSD17B10CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3974166-A | FUNGICIDE | CIBA-GEIGY CORPORATION (US) | 1976-08-10 | — | — | US | claimed |
| US-4521603-A | Continuous process for the production of polybromopyridine compounds | OLIN CORPORATION (US) | 1985-06-04 | — | — | US | disclosed |
| US-3974166-A | FUNGICIDE | CIBA-GEIGY CORPORATION (US) | 1976-08-10 | — | — | US | disclosed |