Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.39 |
| ▸ | PGK1 | P00558 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19814093 | 0.79 | MERTK (0.41) | TSHRMAPK1PDE7ATDP1PGK1 | |
| SCHEMBL25624229 | 0.76 | CYP1A2 (0.53) | TSHRTDP1GPR35ALDH1A1CYP3A4 | |
| SCHEMBL11002997 | 0.76 | ALDH1A1 (0.46) | TSHRMAPK1GPR35PGK1ALDH1A1 | |
| SCHEMBL11005336 | 0.73 | SNCA (0.35) | TSHRPGK1ALDH1A1CYP3A4MAPT | |
| SCHEMBL29783588 | 0.73 | TSHR (0.56) | TSHRMAPK1PDE7ATDP1GPR35 | |
| SCHEMBL9180125 | 0.73 | TSHR (0.62) | TSHRMAPK1TDP1GPR35PGK1 | |
| SCHEMBL3240210 | 0.73 | TSHR (0.56) | TSHRMAPK1PDE7ATDP1GPR35 | |
| SCHEMBL3897956 | 0.72 | PDE7A (0.53) | TSHRMAPK1PDE7ATDP1GPR35 | |
| SCHEMBL30733173 | 0.72 | PDE7A (0.53) | TSHRMAPK1PDE7ATDP1GPR35 | |
| SCHEMBL11000883 | 0.72 | CYP3A4 (0.37) | TSHRMAPK1TDP1CYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4521603-A | Continuous process for the production of polybromopyridine compounds | OLIN CORPORATION (US) | 1985-06-04 | — | — | US | disclosed |
| US-3974166-A | FUNGICIDE | CIBA-GEIGY CORPORATION (US) | 1976-08-10 | — | — | US | disclosed |