SCHEMBL110055

SCHEMBL110055

CC(C)COc1ccccc1N

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.61
CYP2C19 P33261 2/20 0.55
CYP1A2 P05177 1/20 0.55
CYP2C9 P11712 1/20 0.55
GAA P10253 1/20 0.52
TLR8 Q9NR97 1/20 0.51
ADRA2B P18089 1/20 0.50
PTGS1 P23219 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
HTR2C P28335 1/20 0.47
APP P05067 1/20 0.46
LMNA P02545 1/20 0.44
RECQL P46063 1/20 0.44
XDH P47989 1/20 0.41
SCN4A P35499 2/20 0.41
PDE5A O76074 1/20 0.40
PDE4A P27815 1/20 0.40
PDE4B Q07343 1/20 0.40
PDE4C Q08493 1/20 0.40
PDE4D Q08499 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aniline SCHEMBL22169091 0.93 ALDH1A1 (0.53) ALDH1A1CYP2C19CYP1A2CYP2C9GAA
SCHEMBL4334443 0.84 ALDH1A1 (0.55) ALDH1A1CYP1A2GAATLR8HTR2C
SCHEMBL10629706 0.84 ALDH1A1 (0.57) ALDH1A1CYP2C19CYP1A2CYP2C9ADRA2B
SCHEMBL11455939 0.82 ALDH1A1 (0.55) ALDH1A1CYP2C19CYP1A2CYP2C9GAA
SCHEMBL28486036 0.82 ALDH1A1 (0.47) ALDH1A1CYP2C19CYP1A2CYP2C9GAA
SCHEMBL27906166 0.82 ALDH1A1 (0.47) ALDH1A1CYP2C19CYP1A2CYP2C9GAA
SCHEMBL9228456 0.81 ALDH1A1 (0.46) ALDH1A1CYP2C19CYP1A2CYP2C9GAA
SCHEMBL13537826 0.81 ALDH1A1 (0.46) ALDH1A1CYP2C19CYP1A2CYP2C9GAA
SCHEMBL10437693 0.81 ALDH1A1 (0.53) ALDH1A1CYP2C19CYP1A2CYP2C9GAA
SCHEMBL7927132 0.81 ALDH1A1 (0.53) ALDH1A1CYP2C19CYP1A2CYP2C9GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118416038-B Application of 2- (2-methylpropyloxy) aniline in preparation of medicines for treating inflammatory diseases 中国海洋大学 2024-11-12 CN claimed
CN-118416038-A Application of 2- (2-methylpropyloxy) aniline in preparation of medicines for treating inflammatory diseases 中国海洋大学 2024-08-02 CN claimed
WO-2009143405-A2 SYNTHESIS OF GRAPHENE SHEETS AND NANOPARTICLE COMPOSITES COMPRISING SAME THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2009-11-26 WO claimed
CN-118416038-B Application of 2- (2-methylpropyloxy) aniline in preparation of medicines for treating inflammatory diseases 中国海洋大学 2024-11-12 CN disclosed
CN-118416038-B Application of 2- (2-methylpropyloxy) aniline in preparation of medicines for treating inflammatory diseases 中国海洋大学 2024-11-12 CN disclosed
CN-118416038-B Application of 2- (2-methylpropyloxy) aniline in preparation of medicines for treating inflammatory diseases 中国海洋大学 2024-11-12 CN disclosed
CN-118416038-A Application of 2- (2-methylpropyloxy) aniline in preparation of medicines for treating inflammatory diseases 中国海洋大学 2024-08-02 CN disclosed
CN-118416038-A Application of 2- (2-methylpropyloxy) aniline in preparation of medicines for treating inflammatory diseases 中国海洋大学 2024-08-02 CN disclosed
CN-118416038-A Application of 2- (2-methylpropyloxy) aniline in preparation of medicines for treating inflammatory diseases 中国海洋大学 2024-08-02 CN disclosed
CN-111718332-B 2-substituted pyrazol amino-4-substituted amino-5-pyrimidine formamide compound, composition and application thereof 北京赛特明强医药科技有限公司 2021-08-17 CN disclosed
CN-111718332-A 2-substituted pyrazol amino-4-substituted amino-5-pyrimidine formamide compound, composition and application thereof 北京赛特明强医药科技有限公司 2020-09-29 CN disclosed
US-4987258-A Intermediates for disazo dyes HOECHST AKTIENGESELLSCHAFT (DE) 1991-01-22 US disclosed
EP-0196574-B1 4,4'-DIAMINODIPHENYL COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1990-10-10 EP disclosed
EP-0362729-A1 Process for producing water insoluble azo dyes on the fibre HOECHST AKTIENGESELLSCHAFT (DE) 1990-04-11 EP disclosed
EP-0144730-B1 2-ANILINO-1,6-DIHYDRO-6-OXO-5-PYRIMIDINECARBOXYLIC ACID DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF, AND ANTIALLERGIC AGENT CONTAINING THE SAME MORISHITA PHARMACEUTICAL CO. LTD. (JP) 1987-07-08 EP disclosed
EP-0196574-A2 4,4'-Diaminodiphenyl compounds, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1986-10-08 EP disclosed
EP-0144730-A1 2-Anilino-1,6-dihydro-6-oxo-5-pyrimidinecarboxylic acid derivatives, processes for the preparation thereof, and antiallergic agent containing the same MORISHITA PHARMACEUTICAL CO. LTD. (JP) 1985-06-19 EP disclosed
US-4423247-A AMINOALKYLATION, NONCATALYTIC REACTION BASF AKTIENGESELLSCHAFT (DE) 1983-12-27 US disclosed
US-4067903-A Manufacture of arylamines BASF AKTIENGESELLSCHAFT (DT) 1978-01-10 US disclosed
US-3951944-A Fiber-reactive, water-soluble disazo dyes containing an N-B-sulfoethylamide group HOECHST AKTIENGESELLSCHAFT (DT) 1976-04-20 US disclosed