SCHEMBL27906166

SCHEMBL27906166

CC(C)COc1cccc(N)c1OCC(C)C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.47
GAA P10253 1/20 0.47
TLR8 Q9NR97 1/20 0.44
SCN4A P35499 7/20 0.42
CYP1A2 P05177 3/20 0.42
LMNA P02545 2/20 0.42
SCN1A P35498 2/20 0.42
SCN5A Q14524 2/20 0.42
SCN9A Q15858 2/20 0.42
CYP3A4 P08684 2/20 0.42
CYP2D6 P10635 2/20 0.42
NFKB1 P19838 2/20 0.42
CYP2C9 P11712 2/20 0.42
TSHR P16473 1/20 0.42
KCNK3 O14649 1/20 0.42
CACNA1F O60840 1/20 0.42
KCNK2 O95069 1/20 0.42
GBA1 P04062 1/20 0.42
MAOA P21397 1/20 0.42
HTR2A P28223 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6157353 0.86 ALDH1A1 (0.46) ALDH1A1GAATLR8SCN4ACYP1A2
SCHEMBL10633149 0.86 CYP2C19 (0.47) ALDH1A1SCN4ACYP1A2LMNASCN1A
SCHEMBL110055 0.82 ALDH1A1 (0.61) ALDH1A1GAATLR8SCN4ACYP1A2
SCHEMBL28486036 0.81 ALDH1A1 (0.47) ALDH1A1GAATLR8SCN4ACYP1A2
SCHEMBL7927132 0.80 ALDH1A1 (0.53) ALDH1A1GAATLR8SCN4ACYP1A2
SCHEMBL9228456 0.80 ALDH1A1 (0.46) ALDH1A1GAATLR8CYP1A2NFKB1
SCHEMBL13537826 0.80 ALDH1A1 (0.46) ALDH1A1GAATLR8CYP1A2NFKB1
SCHEMBL10437701 0.80 ALDH1A1 (0.42) ALDH1A1GAATLR8SCN4ACYP1A2
SCHEMBL10633258 0.80 TSHR (0.43) ALDH1A1CYP1A2LMNATSHRCYP2C19
SCHEMBL4961658 0.78 NFKB1 (0.48) ALDH1A1GAATLR8SCN4ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102911972-B Preparation method of algistatic active substance di-isobutoxyphenyl amine UNIV XIAMEN 2015-01-21 CN disclosed
CN-102911972-B Preparation method of algistatic active substance di-isobutoxyphenyl amine UNIV XIAMEN 2015-01-21 CN disclosed
CN-102911972-A Preparation method of algistatic active substance di-isobutoxyphenyl amine UNIV XIAMEN 2013-02-06 CN disclosed
CN-102911972-A Preparation method of algistatic active substance di-isobutoxyphenyl amine UNIV XIAMEN 2013-02-06 CN disclosed